Showing entry for Folylpolyglutamate synthase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012845
Protein NameFolylpolyglutamate synthase, mitochondrial
Uniport IdQ05932
GeneFPGS
Gene Id2356
Domain-
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0007420 brain development
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0009396 folic acid-containing compound biosynthetic process
Biological Process GO:0006760 folic acid-containing compound metabolic process
Biological Process GO:0046655 folic acid metabolic process
Biological Process GO:0006536 glutamate metabolic process
Biological Process GO:0001889 liver development
Biological Process GO:0006139 nucleobase-containing compound metabolic process
Biological Process GO:0006730 one-carbon metabolic process
Biological Process GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process
molecular function GO:0005524 ATP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004326 tetrahydrofolylpolyglutamate synthase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005743 mitochondrial inner membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0008924 BXGD000574 Cleft upper lip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0016412 BXGD001058 Folic Acid Deficiency Nutritional and Metabolic Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023453 BXGD001652 L2 Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024302 BXGD001760 Reticulosarcoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024304 BXGD001762 Lymphoma, Mixed-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024306 BXGD001764 Lymphoma, Undifferentiated Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0041296 BXGD002903 Tuberculosis Infections
C0079740 BXGD003088 High Grade Lymphoma (neoplasm) Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079741 BXGD003089 Lymphoma, Intermediate-Grade Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079747 BXGD003093 Low Grade Lymphoma (neoplasm) Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079757 BXGD003095 Diffuse Mixed-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079770 BXGD003098 Lymphoma, Small Noncleaved-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2063389 BXGD016904 Retroperitoneal liposarcoma Neoplasms
C3714542 BXGD019413 Lymphoma, Diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4321245 BXGD022744 Cleft lip or lips
C4721532 BXGD023752 Lymphoma, Non-Hodgkin, Familial Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006162 L-Glutamic acid 147.13
BXGC0007530 Folic acid 441.4
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein