Showing entry for Metastatic human epidermal growth factor 2 positive carcinoma of breast


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023734
Disease NameMetastatic human epidermal growth factor 2 positive carcinoma of breast
Disease CUI IdC4721209
MeSH Codes C04   C17  
Disease Class NameNeoplasms; Skin and Connective Tissue Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P19367 BXGT008476 Hexokinase-1 3098 reviewed Kinase
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49368 BXGT010701 T-complex protein 1 subunit gamma 7203 reviewed Chaperone
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q9Y5K2 BXGT022293 Kallikrein-4 9622 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease