Showing entry for T-complex protein 1 subunit gamma


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010701
Protein NameT-complex protein 1 subunit gamma
Uniport IdP49368
GeneCCT3
Gene Id7203
DomainCpn60_TCP1
Pfam PF00118  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007339 binding of sperm to zona pellucida
Biological Process GO:0046931 pore complex assembly
Biological Process GO:1904851 positive regulation of establishment of protein localization to telomere
Biological Process GO:1904871 positive regulation of protein localization to Cajal body
Biological Process GO:1904874 positive regulation of telomerase RNA localization to Cajal body
Biological Process GO:0032212 positive regulation of telomere maintenance via telomerase
Biological Process GO:0006457 protein folding
Biological Process GO:0050821 protein stabilization
Biological Process GO:1901998 toxin transport
molecular function GO:0005524 ATP binding
molecular function GO:0003723 RNA binding
molecular function GO:0051082 unfolded protein binding
cellular component GO:0044297 cell body
cellular component GO:0005832 chaperonin-containing T-complex
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0005874 microtubule
cellular component GO:0005886 plasma membrane
cellular component GO:0002199 zona pellucida receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC
R-HSA-389958 Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC
R-HSA-390450 Folding of actin by CCT/TriC
R-HSA-390466 Chaperonin-mediated protein folding
R-HSA-390466 Chaperonin-mediated protein folding
R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis
R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis
R-HSA-391251 Protein folding
R-HSA-391251 Protein folding
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-5617833 Cilium Assembly
R-HSA-5620920 Cargo trafficking to the periciliary membrane
R-HSA-5620922 BBSome-mediated cargo-targeting to cilium
R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0014772 BXGD000948 Red Blood Cell Count measurement
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0234958 BXGD004702 Muscle degeneration Musculoskeletal Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0553604 BXGD009402 Myotonic Disorders Musculoskeletal Diseases; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1299884 BXGD012265 Eosinophilic myositis (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931689 BXGD018049 Dystrophia myotonica 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2986665 BXGD018237 Early-Stage Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4721208 BXGD023733 Metastatic castration-resistant prostate cancer
C4721209 BXGD023734 Metastatic human epidermal growth factor 2 positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4755301 BXGD024093 Idiopathic eosinophilic myositis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein