adisease

Showing entry for Advanced Melanoma

General Disease Information
BXGD Id	BXGD023874
Disease Name	Advanced Melanoma
Disease CUI Id	C4727838
MeSH Codes
Disease Class Name
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O95235	BXGT005360	Kinesin-like protein KIF20A	10112	reviewed	Cellular structure
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P10398	BXGT007564	Serine/threonine-protein kinase A-Raf	369	reviewed	Kinase
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61006	BXGT011345	Ras-related protein Rab-8A	4218	reviewed
Q00536	BXGT012535	Cyclin-dependent kinase 16	5127	reviewed	Kinase
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q08499	BXGT012988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	5144	reviewed
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q13007	BXGT023883	Interleukin-24	11009	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}