Showing entry for Forkhead box protein N1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004155
Protein NameForkhead box protein N1
Uniport IdO15353
GeneFOXN1
Gene Id8456
DomainForkhead
Pfam PF00250  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0048514 blood vessel morphogenesis
Biological Process GO:0006952 defense response
Biological Process GO:0008544 epidermis development
Biological Process GO:0001942 hair follicle development
Biological Process GO:0030216 keratinocyte differentiation
Biological Process GO:0097535 lymphoid lineage cell migration into thymus
Biological Process GO:0035878 nail development
Biological Process GO:0030858 positive regulation of epithelial cell differentiation
Biological Process GO:0051798 positive regulation of hair follicle development
Biological Process GO:1902232 regulation of positive thymic T cell selection
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0043029 T cell homeostasis
Biological Process GO:0002360 T cell lineage commitment
Biological Process GO:0097536 thymus epithelium morphogenesis
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0043565 sequence-specific DNA binding
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0002170 BXGD000105 Alopecia Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0002902 BXGD000154 Anencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0012236 BXGD000772 DiGeorge Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0014458 BXGD000916 Eosinophilia, Tropical Hemic and Lymphatic Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0022603 BXGD001565 Seborrheic keratosis Skin and Connective Tissue Diseases
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0040115 BXGD002841 Thymus Hyperplasia Hemic and Lymphatic Diseases
C0080178 BXGD003107 Spina Bifida Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0085110 BXGD003126 Severe Combined Immunodeficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Immune System Diseases
C0150993 BXGD003405 Pitting of nails Skin and Connective Tissue Diseases
C0221260 BXGD004424 Dystrophia unguium Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0235864 BXGD004780 Congenital hypertrichosis lanuginosa Skin and Connective Tissue Diseases
C0263505 BXGD005318 Alopecia universalis Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0265354 BXGD005529 CHARGE Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0265992 BXGD005599 alopecia congenita Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0392485 BXGD008049 Congenital diverticulum of pharynx Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0423820 BXGD008514 Ridged nails
C0477325 BXGD008999 Immunodeficiency associated with other specified major defects
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0685891 BXGD009824 Congenital hypoplasia of thymus Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0685894 BXGD009825 Congenital absence of thymus Immune System Diseases
C0858699 BXGD011187 Skin keratosis Skin and Connective Tissue Diseases
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1321551 BXGD012436 Shprintzen-Goldberg syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Cardiovascular Diseases
C1368683 BXGD012900 Epithelioma Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1737250 BXGD013725 Progression of non-small cell lung cancer
C1849075 BXGD015002 Relative macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1866426 BXGD016398 T-cell immunodeficiency, congenital alopecia and nail dystrophy Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Immune System Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2931322 BXGD018003 T-Lymphocytopenia Immune System Diseases; Hemic and Lymphatic Diseases
C2936812 BXGD018140 Congenital hypertrichosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C3495530 BXGD018990 Congenital alopecia X-linked Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C4024723 BXGD021386 Decreased proportion circulating T-helper cells Immune System Diseases; Hemic and Lymphatic Diseases
C4025175 BXGD021576 Congenital alopecia totalis
C4025208 BXGD021591 Severe T-cell immunodeficiency
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein