adisease

Showing entry for Ductal Carcinoma

General Disease Information
BXGD Id	BXGD011798
Disease Name	Ductal Carcinoma
Disease CUI Id	C1176475
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15353	BXGT004155	Forkhead box protein N1	8456	reviewed
O43255	BXGT004579	E3 ubiquitin-protein ligase SIAH2	6478	reviewed
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43570	BXGT004601	Carbonic anhydrase 12	771	reviewed
O43791	BXGT004626	Speckle-type POZ protein	8405	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04075	BXGT006145	Fructose-bisphosphate aldolase A	226	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05787	BXGT006385	Keratin, type II cytoskeletal 8	3856	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08670	BXGT006810	Vimentin	7431	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12830	BXGT007852	Cadherin-1	999	reviewed
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18075	BXGT008375	Bone morphogenetic protein 7	655	reviewed	Signaling
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P25311	BXGT009036	Zinc-alpha-2-glycoprotein	563	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30101	BXGT009402	Protein disulfide-isomerase A3	2923	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49023	BXGT010672	Paxillin	5829	reviewed	Cellular structure
P49711	BXGT010728	Transcriptional repressor CTCF	10664	reviewed	Transcription factor
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P56937	BXGT011205	3-keto-steroid reductase	51478	reviewed
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P68104	BXGT011575	Elongation factor 1-alpha 1	1915	reviewed	Enzyme
P78358	BXGT011838	Cancer/testis antigen 1	246100	reviewed
Q04724	BXGT012778	Transducin-like enhancer protein 1	7088	reviewed	Transcription factor
Q05513	BXGT012820	Protein kinase C zeta type	5590	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q12797	BXGT013266	Aspartyl/asparaginyl beta-hydroxylase	444	reviewed
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q15084	BXGT013536	Protein disulfide-isomerase A6	10130	reviewed
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16658	BXGT013651	Fascin	6624	reviewed	Cellular structure
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q7Z7D3	BXGT017262	V-set domain-containing T-cell activation inhibitor 1	79679	reviewed	Enzyme modulator
Q8NEM0	BXGT018555	Microcephalin	79648	reviewed	Nucleic acid binding
Q92547	BXGT019355	DNA topoisomerase 2-binding protein 1	11073	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99519	BXGT019928	Sialidase-1	4758	reviewed	Enzyme
Q99527	BXGT019930	G-protein coupled estrogen receptor 1	2852	reviewed	G-protein coupled receptor
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q99828	BXGT019967	Calcium and integrin-binding protein 1	10519	reviewed
Q9BR01	BXGT020115	Sulfotransferase 4A1	25830	reviewed
Q9BUB5	BXGT020133	MAP kinase-interacting serine/threonine-protein kinase 1	8569	reviewed	Kinase
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBB5	BXGT021649	Methyl-CpG-binding domain protein 2	8932	reviewed	Epigenetic regulator
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UQB9	BXGT021810	Aurora kinase C	6795	reviewed	Kinase
Q9Y5K3	BXGT022294	Choline-phosphate cytidylyltransferase B	9468	reviewed
Q9Y6Q9	BXGT022338	Nuclear receptor coactivator 3	8202	reviewed	Kinase
O60936	BXGT022857	Nucleolar protein 3	8996	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q9HAU4	BXGT024040	E3 ubiquitin-protein ligase SMURF2	64750	reviewed	Enzyme
P21926	BXGT024578	CD9 antigen	928	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}