adisease

Showing entry for Thymoma

General Disease Information
BXGD Id	BXGD002840
Disease Name	Thymoma
Disease CUI Id	C0040100
MeSH Codes	C04 C15
Disease Class Name	Neoplasms; Hemic and Lymphatic Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0000818 HP:0002715 HP:0002664 HP:0001626
Human Phenotype Ontology Term	Abnormality of the endocrine system; Abnormality of the immune system; Neoplasm; Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7 DOID:14566
Disease Ontology Class Name	disease of anatomical entity; disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00255	BXGT003903	Menin	4221	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15353	BXGT004155	Forkhead box protein N1	8456	reviewed
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
O60911	BXGT004909	Cathepsin L2	1515	reviewed	Enzyme
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95786	BXGT005396	Probable ATP-dependent RNA helicase DDX58	23586	reviewed
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02144	BXGT005853	Myoglobin	4151	reviewed
P02708	BXGT005927	Acetylcholine receptor subunit alpha	1134	reviewed	Ion channel
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P03951	BXGT006117	Coagulation factor XI	2160	reviewed	Enzyme
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06239	BXGT006427	Tyrosine-protein kinase Lck	3932	reviewed	Kinase
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12830	BXGT007852	Cadherin-1	999	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16070	BXGT008186	CD44 antigen	960	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P23443	BXGT008866	Ribosomal protein S6 kinase beta-1	6198	reviewed	Kinase
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P25325	BXGT009038	3-mercaptopyruvate sulfurtransferase	4357	reviewed	Enzyme
P25791	BXGT009072	Rhombotin-2	4005	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41279	BXGT010254	Mitogen-activated protein kinase kinase kinase 8	1326	reviewed	Kinase
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49888	BXGT010756	Estrogen sulfotransferase	6783	reviewed
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P51532	BXGT010852	Transcription activator BRG1	6597	reviewed	Epigenetic regulator
P51692	BXGT010885	Signal transducer and activator of transcription 5B	6777	reviewed	Nucleic acid binding
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P56937	BXGT011205	3-keto-steroid reductase	51478	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62753	BXGT011454	40S ribosomal protein S6	6194	reviewed	Nucleic acid binding
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	8140	reviewed	Transporter
Q02779	BXGT012670	Mitogen-activated protein kinase kinase kinase 10	4294	reviewed	Kinase
Q04844	BXGT012789	Acetylcholine receptor subunit epsilon	1145	reviewed	Ion channel
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q29980	BXGT013981	MHC class I polypeptide-related sequence B	4277	reviewed
Q30154	BXGT014296	HLA class II histocompatibility antigen, DR beta 5 chain	3127	reviewed	Immune response
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q86T13	BXGT017603	C-type lectin domain family 14 member A	161198	reviewed
Q86U86	BXGT017611	Protein polybromo-1	55193	reviewed	Epigenetic regulator
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92736	BXGT019367	Ryanodine receptor 2	6262	reviewed	Ion channel
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96GD4	BXGT019667	Aurora kinase B	9212	reviewed	Kinase
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q96T88	BXGT019747	E3 ubiquitin-protein ligase UHRF1	29128	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BX66	BXGT020158	Sorbin and SH3 domain-containing protein 1	10580	reviewed
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y6E0	BXGT022327	Serine/threonine-protein kinase 24	8428	reviewed	Kinase
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
Q92922	BXGT023066	SWI/SNF complex subunit SMARCC1	6599	reviewed	Enzyme
Q13330	BXGT023103	Metastasis-associated protein MTA1	9112	reviewed	Nucleic acid binding
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
Q8NEZ4	BXGT024850	Histone-lysine N-methyltransferase 2C	58508	reviewed
Q96MS0	BXGT025241	Roundabout homolog 3	64221	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}