Showing entry for Small glutamine-rich tetratricopeptide repeat-containing protein alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT004621
Protein NameSmall glutamine-rich tetratricopeptide repeat-containing protein alpha
Uniport IdO43765
GeneSGTA
Gene Id6449
DomainSGTA_dimer; TPR_1; TPR_8
Pfam PF16546   PF00515   PF13181  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process
Biological Process GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
Biological Process GO:1903646 positive regulation of chaperone-mediated protein folding
Biological Process GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process
Biological Process GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane
Biological Process GO:0071816 tail-anchored membrane protein insertion into ER membrane
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
Biological Process GO:0016032 viral process
molecular function GO:1904288 BAT3 complex binding
molecular function GO:0042802 identical protein binding
molecular function GO:0060090 molecular adaptor activity
molecular function GO:0043621 protein self-association
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0098850 extrinsic component of synaptic vesicle membrane
cellular component GO:0016020 membrane
cellular component GO:0005634 nucleus
cellular component GO:0072380 TRC complex
Reactome
Pathway Id Pathway Name
R-HSA-9609507 Protein localization
R-HSA-9609507 Protein localization
R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0023290 BXGD001631 Leishmaniasis, Visceral Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0206694 BXGD004245 Mucoepidermoid Carcinoma Neoplasms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0334392 BXGD007055 Epithelial-myoepithelial carcinoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0751569 BXGD010504 Genitourinary Cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1275278 BXGD012074 Extraskeletal Myxoid Chondrosarcoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1654637 BXGD013484 androgen independent prostate cancer
C2062441 BXGD016897 Influenza A
C4048329 BXGD021904 Immunosuppression
C4687546 BXGD023580 Metastatic Genitourinary System Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein