adisease

Showing entry for Tumor Immunity

General Disease Information
BXGD Id	BXGD013244
Disease Name	Tumor Immunity
Disease CUI Id	C1519680
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O14920	BXGT004110	Inhibitor of nuclear factor kappa-B kinase subunit beta	3551	reviewed	Kinase
O14939	BXGT004115	Phospholipase D2	5338	reviewed
O15075	BXGT004124	Serine/threonine-protein kinase DCLK1	9201	reviewed	Kinase
O15389	BXGT004161	Sialic acid-binding Ig-like lectin 5	8778	reviewed	Receptor
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
O43765	BXGT004621	Small glutamine-rich tetratricopeptide repeat-containing protein alpha	6449	reviewed
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
O60341	BXGT004873	Lysine-specific histone demethylase 1A	23028	reviewed	Epigenetic regulator
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11309	BXGT007685	Serine/threonine-protein kinase pim-1	5292	reviewed	Kinase
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13688	BXGT007943	Carcinoembryonic antigen-related cell adhesion molecule 1	634	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15151	BXGT008089	Poliovirus receptor	5817	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15813	BXGT008158	Antigen-presenting glycoprotein CD1d	912	reviewed
P15941	BXGT008176	Mucin-1	4582	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P17676	BXGT008327	CCAAT/enhancer-binding protein beta	1051	reviewed	Transcription factor
P17706	BXGT008330	Tyrosine-protein phosphatase non-receptor type 2	5771	reviewed
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P20591	BXGT008586	Interferon-induced GTP-binding protein Mx1	4599	reviewed	Enzyme modulator
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29317	BXGT009331	Ephrin type-A receptor 2	1969	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41273	BXGT010251	Tumor necrosis factor ligand superfamily member 9	8744	reviewed
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P41743	BXGT010270	Protein kinase C iota type	5584	reviewed	Kinase
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P43489	BXGT010394	Tumor necrosis factor receptor superfamily member 4	7293	reviewed
P46934	BXGT010553	E3 ubiquitin-protein ligase NEDD4	4734	reviewed	Enzyme
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P52789	BXGT010954	Hexokinase-2	3099	reviewed	Kinase
P53350	BXGT010984	Serine/threonine-protein kinase PLK1	5347	reviewed	Kinase
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07011	BXGT012912	Tumor necrosis factor receptor superfamily member 9	3604	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q08334	BXGT012981	Interleukin-10 receptor subunit beta	3588	reviewed	Receptor
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q10589	BXGT013203	Bone marrow stromal antigen 2	684	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q14002	BXGT013433	Carcinoembryonic antigen-related cell adhesion molecule 7	1087	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15257	BXGT013554	Serine/threonine-protein phosphatase 2A activator	5524	reviewed	Enzyme modulator
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q29980	BXGT013981	MHC class I polypeptide-related sequence B	4277	reviewed
Q495A1	BXGT014764	T-cell immunoreceptor with Ig and ITIM domains	201633	reviewed
Q68D85	BXGT016188	Natural cytotoxicity triggering receptor 3 ligand 1	374383	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q7Z7D3	BXGT017262	V-set domain-containing T-cell activation inhibitor 1	79679	reviewed	Enzyme modulator
Q86TM3	BXGT017607	Probable ATP-dependent RNA helicase DDX53	168400	reviewed
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q92831	BXGT019380	Histone acetyltransferase KAT2B	8850	reviewed
Q92956	BXGT019399	Tumor necrosis factor receptor superfamily member 14	8764	reviewed
Q93009	BXGT019455	Ubiquitin carboxyl-terminal hydrolase 7	7874	reviewed	Enzyme
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9BZZ2	BXGT020205	Sialoadhesin	6614	reviewed
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9NR97	BXGT021182	Toll-like receptor 8	51311	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P1W9	BXGT021296	Serine/threonine-protein kinase pim-2	11040	reviewed	Kinase
Q9UBN7	BXGT021658	Histone deacetylase 6	10013	reviewed	Epigenetic regulator
Q9UDY8	BXGT021670	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	10892	reviewed	Enzyme
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UKV8	BXGT021752	Protein argonaute-2	27161	reviewed
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y5A9	BXGT022868	YTH domain-containing family protein 2	51441	reviewed
Q9UNS1	BXGT022882	Protein timeless homolog	8914	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P17535	BXGT023437	Transcription factor jun-D	3727	reviewed	Transcription factor
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
P40198	BXGT023750	Carcinoembryonic antigen-related cell adhesion molecule 3	1084	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q86V25	BXGT024433	Tubulinyl-Tyr carboxypeptidase 2	79805	reviewed
Q7Z6A9	BXGT025024	B- and T-lymphocyte attenuator	151888	reviewed
P25090	BXGT025102	N-formyl peptide receptor 2	2358	reviewed	G-protein coupled receptor
Q9GZV5	BXGT025439	WW domain-containing transcription regulator protein 1	25937	reviewed	Enzyme modulator
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}