Showing entry for Leishmaniasis, Visceral


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001631
Disease NameLeishmaniasis, Visceral
Disease CUI IdC0023290
MeSH Codes C01  
Disease Class NameInfections
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:0050117  
Disease Ontology Class Namedisease of anatomical entity; disease by infectious agent
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O43765 BXGT004621 Small glutamine-rich tetratricopeptide repeat-containing protein alpha 6449 reviewed
O43813 BXGT004628 Glutathione S-transferase LANCL1 10314 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60906 BXGT004908 Sphingomyelin phosphodiesterase 2 6610 reviewed
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06126 BXGT006412 T-cell surface glycoprotein CD1a 909 reviewed
P06239 BXGT006427 Tyrosine-protein kinase Lck 3932 reviewed Kinase
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07237 BXGT006576 Protein disulfide-isomerase 5034 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10153 BXGT007544 Non-secretory ribonuclease 6036 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11926 BXGT007760 Ornithine decarboxylase 4953 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15086 BXGT008078 Carboxypeptidase B 1360 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P20340 BXGT008566 Ras-related protein Rab-6A 5870 reviewed
P23526 BXGT008878 Adenosylhomocysteinase 191 reviewed Enzyme
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26639 BXGT009122 Threonine--tRNA ligase, cytoplasmic 6897 reviewed Enzyme
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30046 BXGT009396 D-dopachrome decarboxylase 1652 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42679 BXGT010328 Megakaryocyte-associated tyrosine-protein kinase 4145 reviewed Kinase
P51665 BXGT010874 26S proteasome non-ATPase regulatory subunit 7 5713 reviewed Enzyme
P53779 BXGT011014 Mitogen-activated protein kinase 10 5602 reviewed Kinase
P54652 BXGT011064 Heat shock-related 70 kDa protein 2 3306 reviewed
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P81172 BXGT011935 Hepcidin 57817 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15485 BXGT013574 Ficolin-2 2220 reviewed Signaling
Q15582 BXGT013581 Transforming growth factor-beta-induced protein ig-h3 7045 reviewed Signaling
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16850 BXGT013681 Lanosterol 14-alpha demethylase 1595 reviewed Enzyme
Q8IXH7 BXGT018359 Negative elongation factor C/D 51497 reviewed
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q92835 BXGT019382 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 3635 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BW92 BXGT020151 Threonine--tRNA ligase, mitochondrial 80222 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9HD26 BXGT020540 Golgi-associated PDZ and coiled-coil motif-containing protein 57120 reviewed
Q9NP99 BXGT021148 Triggering receptor expressed on myeloid cells 1 54210 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYV4 BXGT021262 Cyclin-dependent kinase 12 51755 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9ULC6 BXGT021759 Protein-arginine deiminase type-1 29943 reviewed
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9Y256 BXGT022217 CAAX prenyl protease 2 9986 reviewed Enzyme
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
Q9Y646 BXGT022317 Carboxypeptidase Q 10404 reviewed Enzyme
P35232 BXGT022663 Prohibitin 5245 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P15260 BXGT023924 Interferon gamma receptor 1 3459 reviewed Receptor
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q9BVC4 BXGT026090 Target of rapamycin complex subunit LST8 64223 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease