Showing entry for Plexin-C1



                       
General Target Information
BXGT IdBXGT004877
Protein NamePlexin-C1
Uniport IdO60486
GenePLXNC1
Gene Id10154
DomainPlexin_cytopl; PSI; TIG
Pfam PF08337   PF01437   PF01833  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007162 negative regulation of cell adhesion
Biological Process GO:0050772 positive regulation of axonogenesis
Biological Process GO:0030334 regulation of cell migration
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0043087 regulation of GTPase activity
Biological Process GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance
molecular function GO:0017154 semaphorin receptor activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0002116 semaphorin receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-373755 Semaphorin interactions
R-HSA-416700 Other semaphorin interactions
R-HSA-422475 Axon guidance
R-HSA-9675108 Nervous system development
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0337434 BXGD007157 Estradiol measurement
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0428883 BXGD008639 Diastolic blood pressure
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1443016 BXGD013067 Estradiol level result
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C2985280 BXGD018223 Blood Protein Measurement
C3150797 BXGD018337 AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C4014795 BXGD020166 AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
C4310768 BXGD022658 AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein