Showing entry for Diastolic blood pressure


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD008639
Disease NameDiastolic blood pressure
Disease CUI IdC0428883
MeSH Codes   
Disease Class Name
Semantic TypeClinical Attribute
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60486 BXGT004877 Plexin-C1 10154 reviewed
O60825 BXGT004900 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 5208 reviewed Kinase
O75129 BXGT005101 Astrotactin-2 23245 reviewed
O75643 BXGT005142 U5 small nuclear ribonucleoprotein 200 kDa helicase 23020 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O76082 BXGT005175 Solute carrier family 22 member 5 6584 reviewed Transporter
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O94806 BXGT005335 Serine/threonine-protein kinase D3 23683 reviewed Kinase
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02749 BXGT005941 Beta-2-glycoprotein 1 350 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps 2242 reviewed Kinase
P07947 BXGT006701 Tyrosine-protein kinase Yes 7525 reviewed Kinase
P07948 BXGT006702 Tyrosine-protein kinase Lyn 4067 reviewed Kinase
P08572 BXGT006791 Collagen alpha-2(IV) chain 1284 reviewed
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09958 BXGT006950 Furin 5045 reviewed Enzyme
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P15941 BXGT008176 Mucin-1 4582 reviewed
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17342 BXGT008302 Atrial natriuretic peptide receptor 3 4883 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P19021 BXGT008449 Peptidyl-glycine alpha-amidating monooxygenase 5066 reviewed Enzyme
P19099 BXGT008456 Cytochrome P450 11B2, mitochondrial 1585 reviewed
P19174 BXGT008467 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5335 reviewed Enzyme
P21953 BXGT008711 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 594 reviewed Enzyme
P23468 BXGT008870 Receptor-type tyrosine-protein phosphatase delta 5789 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25786 BXGT009068 Proteasome subunit alpha type-1 5682 reviewed
P26640 BXGT009123 Valine--tRNA ligase 7407 reviewed
P27816 BXGT009209 Microtubule-associated protein 4 4134 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30825 BXGT009469 High affinity cationic amino acid transporter 1 6541 reviewed Transporter
P31152 BXGT009511 Mitogen-activated protein kinase 4 5596 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32239 BXGT009612 Gastrin/cholecystokinin type B receptor 887 reviewed G-protein coupled receptor
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41240 BXGT010242 Tyrosine-protein kinase CSK 1445 reviewed Kinase
P42685 BXGT010332 Tyrosine-protein kinase FRK 2444 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P49802 BXGT010746 Regulator of G-protein signaling 7 6000 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P52569 BXGT010934 Cationic amino acid transporter 2 6542 reviewed Transporter
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P56545 BXGT011178 C-terminal-binding protein 2 1488 reviewed Transcription factor
P61077 BXGT011355 Ubiquitin-conjugating enzyme E2 D3 7323 reviewed Enzyme
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00537 BXGT012536 Cyclin-dependent kinase 17 5128 reviewed Kinase
Q01484 BXGT012592 Ankyrin-2 287 reviewed
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q02108 BXGT012634 Guanylate cyclase soluble subunit alpha-1 2982 reviewed
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q08289 BXGT012979 Voltage-dependent L-type calcium channel subunit beta-2 783 reviewed Ion channel
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q13188 BXGT013324 Serine/threonine-protein kinase 3 6788 reviewed Kinase
Q13639 BXGT013389 5-hydroxytryptamine receptor 4 3360 reviewed G-protein coupled receptor
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14149 BXGT013449 MORC family CW-type zinc finger protein 3 23515 reviewed
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q14576 BXGT013487 ELAV-like protein 3 1995 reviewed
Q14721 BXGT013502 Potassium voltage-gated channel subfamily B member 1 3745 reviewed Ion channel
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q15599 BXGT013583 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 9351 reviewed
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q5SW79 BXGT015843 Centrosomal protein of 170 kDa 9859 reviewed Chaperone
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha 8476 reviewed Kinase
Q5VVQ6 BXGT015888 Ubiquitin thioesterase OTU1 55432 reviewed Enzyme
Q8NEM0 BXGT018555 Microcephalin 79648 reviewed Nucleic acid binding
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8NI77 BXGT018573 Kinesin-like protein KIF18A 81930 reviewed Cellular structure
Q8TDX5 BXGT018816 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 130013 reviewed
Q8TF65 BXGT018825 PDZ domain-containing protein GIPC2 54810 reviewed Enzyme
Q8WTS6 BXGT018986 Histone-lysine N-methyltransferase SETD7 80854 reviewed Epigenetic regulator
Q8WUI4 BXGT018992 Histone deacetylase 7 51564 reviewed Epigenetic regulator
Q8WWQ0 BXGT019003 PH-interacting protein 55023 reviewed Epigenetic regulator
Q92932 BXGT019395 Receptor-type tyrosine-protein phosphatase N2 5799 reviewed
Q96A58 BXGT019614 Ras-related and estrogen-regulated growth inhibitor 85004 reviewed Enzyme modulator
Q96AC1 BXGT019617 Fermitin family homolog 2 10979 reviewed
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q96PU5 BXGT019711 E3 ubiquitin-protein ligase NEDD4-like 23327 reviewed Enzyme
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 79915 reviewed
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BQF6 BXGT020111 Sentrin-specific protease 7 57337 reviewed Enzyme
Q9BV79 BXGT020141 Enoyl-[acyl-carrier-protein] reductase, mitochondrial 51102 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9H0K1 BXGT020438 Serine/threonine-protein kinase SIK2 23235 reviewed Kinase
Q9H8M5 BXGT020496 Metal transporter CNNM2 54805 reviewed
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9HD42 BXGT020543 Charged multivesicular body protein 1a 5119 reviewed
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NY47 BXGT021249 Voltage-dependent calcium channel subunit alpha-2/delta-2 9254 reviewed Ion channel
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 51776 reviewed Kinase
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 10769 reviewed Kinase
Q9P212 BXGT021297 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 51196 reviewed Enzyme
Q9P2K8 BXGT021302 eIF-2-alpha kinase GCN2 440275 reviewed
Q9UBG0 BXGT021654 C-type mannose receptor 2 9902 reviewed
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9UBT6 BXGT021664 DNA polymerase kappa 51426 reviewed
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 51422 reviewed Enzyme modulator
Q9UHX1 BXGT021707 Poly(U)-binding-splicing factor PUF60 22827 reviewed
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q9Y233 BXGT022210 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 10846 reviewed
Q9Y2K2 BXGT022238 Serine/threonine-protein kinase SIK3 23387 reviewed Kinase
Q9Y5P4 BXGT022298 Collagen type IV alpha-3-binding protein 10087 reviewed Transporter
Q9Y618 BXGT022315 Nuclear receptor corepressor 2 9612 reviewed Transcription factor
Q9Y694 BXGT022321 Solute carrier family 22 member 7 10864 reviewed Transporter
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 1456 reviewed Kinase
Q9Y6T7 BXGT022665 Diacylglycerol kinase beta 1607 reviewed Enzyme
O00308 BXGT023349 NEDD4-like E3 ubiquitin-protein ligase WWP2 11060 reviewed Enzyme
Q9ULM3 BXGT023501 YEATS domain-containing protein 2 55689 reviewed Nucleic acid binding
Q9UGC6 BXGT023734 Regulator of G-protein signaling 17 26575 reviewed Enzyme modulator
P46379 BXGT023748 Large proline-rich protein BAG6 7917 reviewed Enzyme modulator
Q9Y255 BXGT024259 PRELI domain-containing protein 1, mitochondrial 27166 reviewed
Q9Y3E1 BXGT024320 Hepatoma-derived growth factor-related protein 3 50810 reviewed Signaling
Q9Y297 BXGT024812 F-box/WD repeat-containing protein 1A 8945 reviewed
Q68CZ6 BXGT025257 HAUS augmin-like complex subunit 3 79441 reviewed
O14649 BXGT025486 Potassium channel subfamily K member 3 3777 reviewed Ion channel
Q9UK61 BXGT025658 Protein TASOR 23272 reviewed
Q96C45 BXGT025705 Serine/threonine-protein kinase ULK4 54986 reviewed Kinase
O14967 BXGT026127 Calmegin 1047 reviewed Chaperone
P09471 BXGT026153 Guanine nucleotide-binding protein G(o) subunit alpha 2775 reviewed Enzyme modulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease