Showing entry for Signal recognition particle subunit SRP72


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005177
Protein NameSignal recognition particle subunit SRP72
Uniport IdO76094
GeneSRP72
Gene Id6731
DomainSRP72; SRP_TPR_like; TPR_8
Pfam PF08492   PF17004   PF13181  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa03060 Protein export
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042493 response to drug
Biological Process GO:0006614 SRP-dependent cotranslational protein targeting to membrane
molecular function GO:0008312 7S RNA binding
molecular function GO:0003723 RNA binding
molecular function GO:0005047 signal recognition particle binding
molecular function GO:0030911 TPR domain binding
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0048500 signal recognition particle
cellular component GO:0005786 signal recognition particle, endoplasmic reticulum targeting
Reactome
Pathway Id Pathway Name
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-72766 Translation
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0002874 BXGD000134 Aplastic Anemia Hemic and Lymphatic Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0026985 BXGD001956 Myelodysplasia
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0085390 BXGD003160 Li-Fraumeni Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1368107 BXGD012895 Aplastic bone marrow Hemic and Lymphatic Diseases
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1611743 BXGD013456 Familial (FPAH)
C1855710 BXGD015534 Bone marrow hypocellularity
C1963099 BXGD016682 Myelodysplasia, CTCAE
C2931245 BXGD017986 Bone Marrow failure syndromes
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3808553 BXGD019550 Bone marrow failure syndrome 1
C3810350 BXGD019651 Bone marrow failure syndrome 2
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002591 Potassium 39.1
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein