adisease

Showing entry for Myelodysplasia

General Disease Information
BXGD Id	BXGD001956
Disease Name	Myelodysplasia
Disease CUI Id	C0026985
MeSH Codes
Disease Class Name
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14727	BXGT004084	Apoptotic protease-activating factor 1	317	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O76094	BXGT005177	Signal recognition particle subunit SRP72	6731	reviewed
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08700	BXGT006816	Interleukin-3	3562	reviewed
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P21583	BXGT008667	Kit ligand	4254	reviewed
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P22830	BXGT008809	Ferrochelatase, mitochondrial	2235	reviewed	Enzyme
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P32320	BXGT009622	Cytidine deaminase	978	reviewed	Enzyme
P35658	BXGT009859	Nuclear pore complex protein Nup214	8021	reviewed	Nucleic acid binding
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	2322	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
Q01081	BXGT012566	Splicing factor U2AF 35 kDa subunit	7307	reviewed
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01196	BXGT012575	Runt-related transcription factor 1	861	reviewed	Transcription factor
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13206	BXGT013326	Probable ATP-dependent RNA helicase DDX10	1662	reviewed
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6PCD5	BXGT016464	E3 ubiquitin-protein ligase RFWD3	55159	reviewed	Enzyme
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IWS0	BXGT018356	PHD finger protein 6	84295	reviewed	Nucleic acid binding
Q8IYD8	BXGT018367	Fanconi anemia group M protein	57697	reviewed	Enzyme
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9BXH1	BXGT020167	Bcl-2-binding component 3	27113	reviewed
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NW38	BXGT021230	E3 ubiquitin-protein ligase FANCL	55120	reviewed	Enzyme
Q9UI95	BXGT021714	Mitotic spindle assembly checkpoint protein MAD2B	10459	reviewed
Q9UJV9	BXGT021731	Probable ATP-dependent RNA helicase DDX41	51428	reviewed
Q9UPY3	BXGT021802	Endoribonuclease Dicer	23405	reviewed	Enzyme
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9NRR4	BXGT025788	Ribonuclease 3	29102	reviewed	Enzyme
P62263	BXGT026033	40S ribosomal protein S14	6208	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}