Showing entry for Monocarboxylate transporter 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005406
Protein NameMonocarboxylate transporter 3
Uniport IdO95907
GeneSLC16A8
Gene Id23539
DomainMFS_1
Pfam PF07690  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015727 lactate transport
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0015718 monocarboxylic acid transport
Biological Process GO:0006090 pyruvate metabolic process
molecular function GO:0015129 lactate transmembrane transporter activity
molecular function GO:0008028 monocarboxylic acid transmembrane transporter activity
molecular function GO:0015293 symporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport
R-HSA-1430728 Metabolism
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-210991 Basigin interactions
R-HSA-382551 Transport of small molecules
R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-433692 Proton-coupled monocarboxylate transport
R-HSA-70268 Pyruvate metabolism
R-HSA-71406 Pyruvate metabolism and Citric Acid (TCA) cycle
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0085136 BXGD003131 Central Nervous System Neoplasms Neoplasms; Nervous System Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C1536085 BXGD013334 Geographic Atrophy Eye Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2237660 BXGD016962 exudative macular degeneration Eye Diseases
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0038275 Pyruvic Acid 88.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein