Showing entry for Age related macular degeneration


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005160
Disease NameAge related macular degeneration
Disease CUI IdC0242383
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00754 BXGT003944 Lysosomal alpha-mannosidase 4125 reviewed
O00755 BXGT003945 Protein Wnt-7a 7476 reviewed Signaling
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O14994 BXGT004120 Synapsin-3 8224 reviewed Cellular structure
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O15553 BXGT004181 Pyrin 4210 reviewed
O43557 BXGT004600 Tumor necrosis factor ligand superfamily member 14 8740 reviewed Signaling
O43708 BXGT004617 Maleylacetoacetate isomerase 2954 reviewed
O43915 BXGT004636 Vascular endothelial growth factor D 2277 reviewed Signaling
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60882 BXGT004905 Matrix metalloproteinase-20 9313 reviewed Enzyme
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 7367 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95445 BXGT005381 Apolipoprotein M 55937 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
O95907 BXGT005406 Monocarboxylate transporter 3 23539 reviewed Transporter
O95954 BXGT005408 Formimidoyltransferase-cyclodeaminase 10841 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00740 BXGT005634 Coagulation factor IX 2158 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01031 BXGT005720 Complement C5 727 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02748 BXGT005940 Complement component C9 735 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P02795 BXGT005968 Metallothionein-2 4502 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03891 BXGT006110 NADH-ubiquinone oxidoreductase chain 2 4536 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04003 BXGT006124 C4b-binding protein alpha chain 722 reviewed
P04004 BXGT006125 Vitronectin 7448 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05156 BXGT006329 Complement factor I 3426 reviewed
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06681 BXGT006468 Complement C2 717 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08100 BXGT006725 Rhodopsin 6010 reviewed G-protein coupled receptor
P08174 BXGT006739 Complement decay-accelerating factor 1604 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08603 BXGT006798 Complement factor H 3075 reviewed
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08670 BXGT006810 Vimentin 7431 reviewed
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10620 BXGT007590 Microsomal glutathione S-transferase 1 4257 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P12271 BXGT007786 Retinaldehyde-binding protein 1 6017 reviewed Transporter
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13051 BXGT007877 Uracil-DNA glycosylase 7374 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14151 BXGT007990 L-selectin 6402 reviewed
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16109 BXGT008194 P-selectin 6403 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17538 BXGT008314 Chymotrypsinogen B 1504 reviewed Enzyme
P17707 BXGT008331 S-adenosylmethionine decarboxylase proenzyme 262 reviewed Enzyme
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19623 BXGT008503 Spermidine synthase 6723 reviewed Enzyme
P20839 BXGT008608 Inosine-5'-monophosphate dehydrogenase 1 3614 reviewed Enzyme
P20851 BXGT008609 C4b-binding protein beta chain 725 reviewed
P21399 BXGT008646 Cytoplasmic aconitate hydratase 48 reviewed Enzyme
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P22223 BXGT008744 Cadherin-3 1001 reviewed
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P24855 BXGT008998 Deoxyribonuclease-1 1773 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27540 BXGT009190 Aryl hydrocarbon receptor nuclear translocator 405 reviewed Transcription factor
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28161 BXGT009234 Glutathione S-transferase Mu 2 2946 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P30519 BXGT009429 Heme oxygenase 2 3163 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30876 BXGT009476 DNA-directed RNA polymerase II subunit RPB2 5431 reviewed Enzyme
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34059 BXGT009749 N-acetylgalactosamine-6-sulfatase 2588 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P34947 BXGT009774 G protein-coupled receptor kinase 5 2869 reviewed Kinase
P35221 BXGT009798 Catenin alpha-1 1495 reviewed Cellular structure
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35398 BXGT009825 Nuclear receptor ROR-alpha 6095 reviewed Nuclear receptor
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42685 BXGT010332 Tyrosine-protein kinase FRK 2444 reviewed Kinase
P43080 BXGT010354 Guanylyl cyclase-activating protein 1 2978 reviewed
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46439 BXGT010523 Glutathione S-transferase Mu 5 2949 reviewed
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P48507 BXGT010636 Glutamate--cysteine ligase regulatory subunit 2730 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P48740 BXGT010659 Mannan-binding lectin serine protease 1 5648 reviewed Enzyme
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P50897 BXGT010823 Palmitoyl-protein thioesterase 1 5538 reviewed Enzyme
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P51878 BXGT010902 Caspase-5 838 reviewed Enzyme
P51993 BXGT010914 Alpha-(1,3)-fucosyltransferase 6 2528 reviewed Enzyme
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P78362 BXGT011839 SRSF protein kinase 2 6733 reviewed Kinase
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
P82279 BXGT011972 Protein crumbs homolog 1 23418 reviewed
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01469 BXGT012590 Fatty acid-binding protein 5 2171 reviewed
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q03468 BXGT012716 DNA excision repair protein ERCC-6 2074 reviewed
Q03692 BXGT012735 Collagen alpha-1(X) chain 1300 reviewed Extracellular structure
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06828 BXGT012893 Fibromodulin 2331 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q12866 BXGT013273 Tyrosine-protein kinase Mer 10461 reviewed Kinase
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13402 BXGT013348 Unconventional myosin-VIIa 4647 reviewed Cellular structure
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14145 BXGT013448 Kelch-like ECH-associated protein 1 9817 reviewed
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15485 BXGT013574 Ficolin-2 2220 reviewed Signaling
Q15554 BXGT013577 Telomeric repeat-binding factor 2 7014 reviewed
Q15599 BXGT013583 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 9351 reviewed
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15751 BXGT013593 Probable E3 ubiquitin-protein ligase HERC1 8925 reviewed Enzyme modulator
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6JQN1 BXGT016338 Acyl-CoA dehydrogenase family member 10 80724 reviewed Enzyme
Q6VVX0 BXGT016585 Vitamin D 25-hydroxylase 120227 reviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8N1Q1 BXGT018499 Carbonic anhydrase 13 377677 reviewed
Q8N4E7 BXGT018511 Ferritin, mitochondrial 94033 reviewed Storage
Q8WWY3 BXGT019006 U4/U6 small nuclear ribonucleoprotein Prp31 26121 reviewed Nucleic acid binding
Q8WX39 BXGT019007 Epididymal-specific lipocalin-9 392399 reviewed
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92598 BXGT019356 Heat shock protein 105 kDa 10808 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q92781 BXGT019372 Retinol dehydrogenase 5 5959 reviewed Enzyme
Q92784 BXGT019373 Zinc finger protein DPF3 8110 reviewed Enzyme
Q92834 BXGT019381 X-linked retinitis pigmentosa GTPase regulator 6103 reviewed
Q92918 BXGT019394 Mitogen-activated protein kinase kinase kinase kinase 1 11184 reviewed Kinase
Q969R2 BXGT019611 Oxysterol-binding protein 2 23762 reviewed
Q96AT9 BXGT019619 Ribulose-phosphate 3-epimerase 6120 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96DB2 BXGT019639 Histone deacetylase 11 79885 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96F46 BXGT019656 Interleukin-17 receptor A 23765 reviewed
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 57787 reviewed Kinase
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9BWD1 BXGT020152 Acetyl-CoA acetyltransferase, cytosolic 39 reviewed Enzyme
Q9BXA5 BXGT020163 Succinate receptor 1 56670 reviewed G-protein coupled receptor
Q9BXJ0 BXGT020169 Complement C1q tumor necrosis factor-related protein 5 114902 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H0J9 BXGT020437 Protein mono-ADP-ribosyltransferase PARP12 64761 reviewed
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9HB21 BXGT020513 Pleckstrin homology domain-containing family A member 1 59338 reviewed Epigenetic regulator
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NW15 BXGT021229 Anoctamin-10 55129 reviewed
Q9NXG6 BXGT021246 Transmembrane prolyl 4-hydroxylase 54681 reviewed
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NYR8 BXGT021261 Retinol dehydrogenase 8 50700 reviewed Enzyme
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UKJ1 BXGT021744 Paired immunoglobulin-like type 2 receptor alpha 29992 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y4I1 BXGT022278 Unconventional myosin-Va 4644 reviewed Cellular structure
Q9Y5X4 BXGT022306 Photoreceptor-specific nuclear receptor 10002 reviewed Nuclear receptor
Q9Y6A2 BXGT022324 Cholesterol 24-hydroxylase 10858 reviewed Enzyme
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 10599 reviewed Transporter
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
O60359 BXGT022652 Voltage-dependent calcium channel gamma-3 subunit 10368 reviewed Ion channel
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
Q5JP69 BXGT022691 C3/C5 convertase 717 unreviewed
Q96KN7 BXGT022801 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 57096 reviewed Enzyme modulator
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UK05 BXGT023094 Growth/differentiation factor 2 2658 reviewed Signaling
Q01955 BXGT023255 Collagen alpha-3(IV) chain 1285 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
O14490 BXGT023570 Disks large-associated protein 1 9229 reviewed Receptor
Q59FF6 BXGT023693 Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant 2074 unreviewed
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
P27918 BXGT025485 Properdin 5199 reviewed
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
Q5BJF2 BXGT026107 Sigma intracellular receptor 2 27346 reviewed Enzyme
P43320 BXGT026151 Beta-crystallin B2 1415 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease