Showing entry for Central Nervous System Neoplasms


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003131
Disease NameCentral Nervous System Neoplasms
Disease CUI IdC0085136
MeSH Codes C04   C10  
Disease Class NameNeoplasms; Nervous System Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0000707   HP:0002664  
Human Phenotype Ontology TermAbnormality of the nervous system; Neoplasm
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O75385 BXGT005121 Serine/threonine-protein kinase ULK1 8408 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95907 BXGT005406 Monocarboxylate transporter 3 23539 reviewed Transporter
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02760 BXGT005948 Protein AMBP 259 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P05090 BXGT006311 Apolipoprotein D 347 reviewed
P07355 BXGT006609 Annexin A2 302 reviewed
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20794 BXGT008600 Serine/threonine-protein kinase MAK 4117 reviewed Kinase
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P24928 BXGT009001 DNA-directed RNA polymerase II subunit RPB1 5430 reviewed Enzyme
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46100 BXGT010508 Transcriptional regulator ATRX 546 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P84243 BXGT012052 Histone H3.3 3021 reviewed
Q05516 BXGT012822 Zinc finger and BTB domain-containing protein 16 7704 reviewed Transcription factor
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q6NUK1 BXGT016429 Calcium-binding mitochondrial carrier protein SCaMC-1 29957 reviewed Transporter
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q8NEB9 BXGT018553 Phosphatidylinositol 3-kinase catalytic subunit type 3 5289 reviewed Kinase
Q8WXI4 BXGT019013 Acyl-coenzyme A thioesterase 11 26027 reviewed Enzyme
Q92796 BXGT019376 Disks large homolog 3 1741 reviewed
Q92830 BXGT019379 Histone acetyltransferase KAT2A 2648 reviewed
Q92831 BXGT019380 Histone acetyltransferase KAT2B 8850 reviewed
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96JA1 BXGT019681 Leucine-rich repeats and immunoglobulin-like domains protein 1 26018 reviewed Receptor
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9H0P0 BXGT020439 Cytosolic 5'-nucleotidase 3A 51251 reviewed Enzyme
Q9H7B4 BXGT020490 Histone-lysine N-methyltransferase SMYD3 64754 reviewed Epigenetic regulator
Q9HD26 BXGT020540 Golgi-associated PDZ and coiled-coil motif-containing protein 57120 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase 10000 reviewed Kinase
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
P35240 BXGT022927 Merlin 4771 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease