Showing entry for Geographic Atrophy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013334
Disease NameGeographic Atrophy
Disease CUI IdC1536085
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000478  
Human Phenotype Ontology TermAbnormality of the eye
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14994 BXGT004120 Synapsin-3 8224 reviewed Cellular structure
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95907 BXGT005406 Monocarboxylate transporter 3 23539 reviewed Transporter
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00751 BXGT005643 Complement factor B 629 reviewed
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02748 BXGT005940 Complement component C9 735 reviewed
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P05156 BXGT006329 Complement factor I 3426 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06681 BXGT006468 Complement C2 717 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08603 BXGT006798 Complement factor H 3075 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17707 BXGT008331 S-adenosylmethionine decarboxylase proenzyme 262 reviewed Enzyme
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20839 BXGT008608 Inosine-5'-monophosphate dehydrogenase 1 3614 reviewed Enzyme
P30533 BXGT009434 Alpha-2-macroglobulin receptor-associated protein 4043 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P51993 BXGT010914 Alpha-(1,3)-fucosyltransferase 6 2528 reviewed Enzyme
P78362 BXGT011839 SRSF protein kinase 2 6733 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q6JQN1 BXGT016338 Acyl-CoA dehydrogenase family member 10 80724 reviewed Enzyme
Q8N884 BXGT018528 Cyclic GMP-AMP synthase 115004 reviewed
Q92743 BXGT019368 Serine protease HTRA1 5654 reviewed Enzyme
Q92781 BXGT019372 Retinol dehydrogenase 5 5959 reviewed Enzyme
Q96AT9 BXGT019619 Ribulose-phosphate 3-epimerase 6120 reviewed
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 57787 reviewed Kinase
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BXJ0 BXGT020169 Complement C1q tumor necrosis factor-related protein 5 114902 reviewed
Q9UKJ1 BXGT021744 Paired immunoglobulin-like type 2 receptor alpha 29992 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q5JP69 BXGT022691 C3/C5 convertase 717 unreviewed
Q01955 BXGT023255 Collagen alpha-3(IV) chain 1285 reviewed
Q5BJF2 BXGT026107 Sigma intracellular receptor 2 27346 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease