Showing entry for Neuronal acetylcholine receptor subunit alpha-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT007809
Protein NameNeuronal acetylcholine receptor subunit alpha-2
Uniport IdP12389
GeneChrna2
Gene Id170945
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0050877 nervous system process
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0035094 response to nicotine
Biological Process GO:0007165 signal transduction
Biological Process GO:0007271 synaptic transmission, cholinergic
molecular function GO:0042166 acetylcholine binding
molecular function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular function GO:0015464 acetylcholine receptor activity
molecular function GO:0008144 drug binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0044877 protein-containing complex binding
cellular component GO:0005892 acetylcholine-gated channel complex
cellular component GO:0071944 cell periphery
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0043005 neuron projection
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000409 Choline 104.17
BXGC0000555 3-Ethylpyridine 107.15
BXGC0001488 Erysodine 299.36
BXGC0001518 (S)-2-Propylpiperidine 127.23
BXGC0001589 Arecoline 155.19
BXGC0002796 Nicotine 162.23
BXGC0002987 2,6-Diemthyl-pyridine 107.15
BXGC0002989 2-Ethylpyridine 107.15
BXGC0002992 2-Methylpyridine 93.13
BXGC0003004 3-Methylpyridine 93.13
BXGC0003010 4-Methylpyridine 93.13
BXGC0003102 Acetylcholine 146.21
BXGC0003128 Cotinine 176.22
BXGC0003965 Prolamine 71.12
BXGC0006243 Piperidine 85.15
BXGC0007675 Pyridine 79.1
BXGC0019419 2-hydroxypyridine 95.04
BXGC0021495 Dl-Anabasine 162.12
BXGC0021636 2-[(2R,6S)-1-Methyl-6-Phenacylpiperidin-2-Yl]-1-Phenylethanone 335.19
BXGC0026677 4-methylpiperidine 99.1
BXGC0035415 R-Nicotine 162.12
BXGC0035631 cytisine 190.11
BXGC0038169 (-)-Lobeline 337.2
BXGC0042179 Atropine 289.17
BXGC0046653 (+/-)Nicotine 162.12
BXGC0049005 (1R)-2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-Phenylethyl]-1-Methylpiperidin-2-Yl]-1-Phenylethanol 339.22
BXGC0050754 Cytisine 190.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein