acompound

Showing entry for Arecoline

General Compound Information
BXGC Id	BXGC0001589
Compound Name	Arecoline
Structure
Formula	C8H13NO2
InchiKey	HJJPJSXJAXAIPN-UHFFFAOYSA-N
SMILES	COC(=O)C1=CCCN(C)C1
Inchi	InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3
IUPAC	methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate
Molecular Weight	155.19
Pubchem Id	2230
Chembl Id	CHEMBL7303

Targets of Information Source

DrugBank

DB04365

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	experimental	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	experimental	-

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

46858

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT018809	Mucolipin-3	reviewed	Ion channel	MCOLN3	-	-	-	2260
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	5950	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	5270	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	4.1	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	1000	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	77	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	1300	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	545	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	1740	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	115	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	115500	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	11000	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	20	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	5600	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	-	-	100
reviewed	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	5.5	-	-	-
reviewed	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	3.3	-	-	-
reviewed	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	-	-	27000
reviewed	BXGT006896	Neuronal acetylcholine receptor subunit alpha-4	reviewed		Chrna4	270	-	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	-	-	-	130
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	-	-	-	600
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	-	-	340
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	-	-	25
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	-	-	3200
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	-	-	83
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	40	-	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	2400	-	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	11000	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	65000	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	-	13500	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	1800	-	-
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	-	62500	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	58000	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	145000	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	4500	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	-	47500	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	26	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	14	-	-	-
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	56000	-	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	43000	-	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	60000	-	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	2400	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	29000	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	86000	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	469000	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	9150	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	11920	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	1000	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	77	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	88000	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	460000	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	24	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	1.9	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	106000	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	-	-	73
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	115	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	25400	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	-	-	-	5603
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	-	-	10000
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	590	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	1100	-	-
reviewed	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed		Chrm3	-	-	-	12000
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	40	-	-	-
reviewed	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed		Chrm4	2400	-	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	5700	-	-	-
reviewed	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed		Chrm3	5700	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	1738	-	-

CHEMBL

CHEMBL7303

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	115	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	115	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	115	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	115	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	115	nM
Q13951	BXGT013407	Core-binding factor subunit beta	reviewed	-	CBFB	Potency	-	19952	nM
Q01196	BXGT012575	Runt-related transcription factor 1	reviewed	Transcription factor	RUNX1	Potency	-	19952	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	11000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	25400	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	25400	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	25400	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	25400	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	25400	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	6	uM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	6	uM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	6	uM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	6	uM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	6	uM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	5	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	469000	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Inhibition	'='	101	%
Q05941	BXGT012847	Neuronal acetylcholine receptor subunit alpha-7	reviewed	-	Chrna7	Ki	'='	224	nM
P20420	BXGT008572	Neuronal acetylcholine receptor subunit alpha-5	reviewed	-	Chrna5	Ki	'='	224	nM
P43143	BXGT010361	Neuronal acetylcholine receptor subunit alpha-6	reviewed	-	Chrna6	Ki	'='	224	nM
P12391	BXGT007811	Neuronal acetylcholine receptor subunit beta-3	reviewed	-	Chrnb3	Ki	'='	224	nM
Q9JLB5	BXGT020832	Neuronal acetylcholine receptor subunit alpha-10	reviewed	-	Chrna10	Ki	'='	224	nM
P43144	BXGT010362	Neuronal acetylcholine receptor subunit alpha-9	reviewed	-	Chrna9	Ki	'='	224	nM
P12392	BXGT007812	Neuronal acetylcholine receptor subunit beta-4	reviewed	-	Chrnb4	Ki	'='	224	nM
P12390	BXGT007810	Neuronal acetylcholine receptor subunit beta-2	reviewed	-	Chrnb2	Ki	'='	224	nM
P12389	BXGT007809	Neuronal acetylcholine receptor subunit alpha-2	reviewed	-	Chrna2	Ki	'='	224	nM
P09483	BXGT006896	Neuronal acetylcholine receptor subunit alpha-4	reviewed	-	Chrna4	Ki	'='	224	nM
P04757	BXGT006258	Neuronal acetylcholine receptor subunit alpha-3	reviewed	-	Chrna3	Ki	'='	224	nM
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Inhibition	'='	35	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	88000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	2454	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
P10828	BXGT007624	Thyroid hormone receptor beta	reviewed	Nuclear receptor	THRB	Potency	'='	35	nM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	28000	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	28000	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	28000	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	28000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	28000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	16	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	16	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	16	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	16	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	16	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	EC50	'='	340	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Max PI	'='	25	%
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	56234	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	222	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	222	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	222	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	222	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	222	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	5600	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	5600	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	5600	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	5600	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	5600	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	40	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ratio	'='	165	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	77	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	29000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	2100	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	2100	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	2100	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	2100	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	2100	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	EC50	'='	3200	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	3	nM
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Inhibition	'='	100	%
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	115	nM
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Inhibition	'='	65	%
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	KL	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	40	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	40	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	40	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	40	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	40	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Max PI	'='	51	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'='	10000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'='	83	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	0	uM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	0	uM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	0	uM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	0	uM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	0	uM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	560	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	560	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	560	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	560	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	560	-
P97697	BXGT012214	Inositol monophosphatase 1	reviewed	-	Impa1	Potency	'='	3548	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	960	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	960	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	960	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	960	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	960	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	87	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	2400	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	'='	11000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1100	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	EC50	'='	27000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ratio	'='	0	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	M2/M1 index	'='	0	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	M2/M1 index	'='	0	-
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	pD2	'='	6	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	77	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	77	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	77	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	77	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	77	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	40	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	20	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	20	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	20	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	20	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	20	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	'='	58000	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Inhibition	'='	13	%
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	545	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	1000	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	1000	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	1000	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	1000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	19000	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	19000	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	19000	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	19000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	19000	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	29512	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	2400	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Inhibition	'='	13	%
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	5	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	5	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	5	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	5	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	5	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	360	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	360	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	360	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	360	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	360	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Inhibition	'='	43	%
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	-	-	-
P25094	BXGT009014	Peripheral myelin protein 22	reviewed	-	Pmp22	Potency	-	40533	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1300	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	106000	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	106000	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	106000	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	106000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	106000	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Max contraction	'='	100	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Max contraction	'='	100	%
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Max contraction	'='	100	%
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Max contraction	'='	100	%
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Max contraction	'='	100	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	'='	4500	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	-	210	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	-	210	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	-	210	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	-	210	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	-	210	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	14	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	26	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	1900	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	1900	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	1900	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	1900	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	1900	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	86000	nM
P12390	BXGT007810	Neuronal acetylcholine receptor subunit beta-2	reviewed	-	Chrnb2	Ki	'='	270	nM
P09483	BXGT006896	Neuronal acetylcholine receptor subunit alpha-4	reviewed	-	Chrna4	Ki	'='	270	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	5700	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Smax	'='	180	%
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	EC50	'='	12000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	2400	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	EC50	'='	600	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	EC50	'>='	220	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Max stimulation	'='	28	%
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Max stimulation	'='	28	%
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Max stimulation	'='	28	%
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Max stimulation	'='	28	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Max stimulation	'='	28	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1740	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Muscarinic agonist index	'='	223	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Muscarinic agonist index	'='	223	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Muscarinic agonist index	'='	223	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Muscarinic agonist index	'='	223	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Muscarinic agonist index	'='	223	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	IC50	'='	47500	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Efficiency	'='	80	%
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Efficiency	'='	80	%
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Efficiency	'='	80	%
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Efficiency	'='	80	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Efficiency	'='	80	%
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Smax	'='	96	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	pD2	'='	6	-
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	KL	'='	0	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Inhibition	'='	99	%
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	62	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	62	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	62	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	62	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	62	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	24	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	24	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	24	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	24	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	24	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	1000	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	3358	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	1000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1737	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	-	-	-
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Km	'='	2	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	145000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	1700	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	1700	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	1700	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	1700	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1700	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	65000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	'='	1800	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	IC50	'='	13500	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'='	25	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	590	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	31	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	31	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	31	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	31	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	31	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	inhibition (at 100uM)	'='	42	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ratio	'='	0	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ratio	'='	0	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	EC50	'='	73	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'='	73	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	EC50	'='	73	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	EC50	'='	73	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	EC50	'='	73	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Efficiency	'='	100	%
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Efficiency	'='	100	%
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Efficiency	'='	100	%
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Efficiency	'='	100	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Efficiency	'='	100	%
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	115500	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ratio	'='	1001	-
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	Efficiency	'='	100	%
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	316	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	460000	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Inhibition	'='	43	%
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Inhibition	'='	43	%
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Inhibition	'='	43	%
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Inhibition	'='	43	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Inhibition	'='	43	%
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	11920	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	9150	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	7120	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	7120	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	7120	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	7120	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	7120	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Max	'='	95	%
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	EC50	'='	100	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	43000	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	IC50	'='	62500	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	120	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	120	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	120	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	120	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	120	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	60000	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	EC50	'='	5603	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Max cAMP	'='	119	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	EC50	'='	140	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	EC50	'='	140	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	25000	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	25000	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	25000	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	25000	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	25000	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	-	-	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	EC50	'='	130	nM
A9XFY4	BXGT001818	Nicotinic acetylcholine receptor alpha 5 subunit	unreviewed	-	nAChRalpha5	Ki	'='	516000	nM
O35505	BXGT004533	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	CACNA1C	IC50	'='	33730	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	1000000	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	5700	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	56000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00821	Nuts		Nuts

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}