acompound

Showing entry for Atropine

General Compound Information
BXGC Id	BXGC0042179
Compound Name	Atropine
Structure
Formula	C17H23NO3
InchiKey	RKUNBYITZUJHSG-SPUOUPEWSA-N
SMILES	OCC(c1ccccc1)C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)N2C
Inchi	InChI=1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
IUPAC
Molecular Weight	289.17
Pubchem Id
Chembl Id	CHEMBL517712

Targets of Information Source

DrugBank

DB00572

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	approved; vet_approved	antagonist
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	approved; vet_approved	antagonist
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	approved; vet_approved	antagonist
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	approved; vet_approved	antagonist
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	approved; vet_approved	antagonist
P23415	BXGT008864	Glycine receptor subunit alpha-1	reviewed	Ion channel	GLRA1	approved; vet_approved	antagonist
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	reviewed	Ion channel	CHRNA4	approved; vet_approved	-
P17787	BXGT008341	Neuronal acetylcholine receptor subunit beta-2	reviewed	Ion channel	CHRNB2	approved; vet_approved	-

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50403547

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.7	-	-	-
reviewed	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.35	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.7	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	0.5	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	1.6	-	-	-
reviewed	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed		Chrm3	-	-	0.63	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	-	2.7	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	-	-	1.3	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.76	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	0.26	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	0.329	-	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	0.344	-	-	-
reviewed	BXGT008694	Acetylcholinesterase	reviewed		Ache	0.7	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	2	-	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	1	-	-	-
reviewed	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed		Htr1a	>20000	-	-	-
reviewed	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed		Chrm3	0.12	-	-	-
reviewed	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed		Chrm1	1.4	-	-	-
reviewed	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	0.3	-	-	-
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	0.4	-	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	1.9	-	-	-
reviewed	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	3	-	-	-
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	1	-	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	0.9	-	-	-
reviewed	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	1.5	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	-	4.8	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	1	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	7.5	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.45	-	-	-
reviewed	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	-	-	0.9	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.459	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.337	-	-	-
reviewed	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed		Chrm2	0.3	-	-	-
reviewed	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	-	-	1.35	-
reviewed	BXGT008694	Acetylcholinesterase	reviewed		Ache	0.35	-	-	-
reviewed	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed		Chrm4	0.56	-	-	-
reviewed	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed		Chrm5	1.8	-	-	-
reviewed	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	-	12200	-	-
reviewed	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed		Chrm4	0.52	-	-	-
reviewed	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed		Chrm5	0.86	-	-	-

CHEMBL

CHEMBL517712

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Kd	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Kd	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Kd	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Kd	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Kd	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	0	uM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	0	uM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	0	uM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	0	uM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	0	uM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	1	nM
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Ki	-	-	-
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	IC50	-	-	-
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	IC50	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	4	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	4	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	4	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	4	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	4	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	0	uM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	0	uM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	0	uM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	0	uM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	0	uM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	2	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	2	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	2	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	2	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	2	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	4100	-
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ratio	'='	4100	-
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ratio	'='	4100	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ratio	'='	4100	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	4100	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kb	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kb	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kb	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kb	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kb	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kb	'='	0	nM
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K 0.5	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	2	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	IC50	'='	0	nM
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	IC50	-	-	-
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	IC50	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Ki	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	IC50	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	Ki	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	IC50	-	-	-
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Ki	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	Ki	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	Ki	-	-	-
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	IC50	-	-	-
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	reviewed	-	SIGMAR1	Ki	-	-	-
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	IC50	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	IC50	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	IC50	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	Ki	-	-	-
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	IC50	-	-	-
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	IC50	-	-	-
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	reviewed	Transporter	ABCC2	Activity	'='	59	%
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	Ki	-	-	-
P25105	BXGT009021	Platelet-activating factor receptor	reviewed	G-protein coupled receptor	PTAFR	Ki	-	-	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	IC50	-	-	-
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	IC50	-	-	-
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	Ki	-	-	-
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	Ki	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	Ki	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	Ki	-	-	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	IC50	-	-	-
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	IC50	-	-	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	2	nM
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	Log B/F	'='	1	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Activity	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	Ki	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	IC50	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	Ki	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	-	-	-
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	IC50	-	-	-
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	Ki	-	-	-
Q64133	BXGT016109	Amine oxidase [flavin-containing] A	reviewed	-	Maoa	Activity	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	reviewed	-	PDE5A	IC50	-	-	-
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	Ki	-	-	-
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	Ki	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	IC50	-	-	-
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	reviewed	Kinase	ERBB2	IC50	-	-	-
P28564	BXGT009272	5-hydroxytryptamine receptor 1B	reviewed	-	Htr1b	IC50	-	-	-
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	IC50	-	-	-
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	Ki	-	-	-
P32241	BXGT009613	Vasoactive intestinal polypeptide receptor 1	reviewed	G-protein coupled receptor	VIPR1	IC50	-	-	-
P27361	BXGT009176	Mitogen-activated protein kinase 3	reviewed	Kinase	MAPK3	IC50	-	-	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	Kd	'='	1	nM
Q05941	BXGT012847	Neuronal acetylcholine receptor subunit alpha-7	reviewed	-	Chrna7	Enhancement	'='	24	%
P20420	BXGT008572	Neuronal acetylcholine receptor subunit alpha-5	reviewed	-	Chrna5	Enhancement	'='	24	%
P43143	BXGT010361	Neuronal acetylcholine receptor subunit alpha-6	reviewed	-	Chrna6	Enhancement	'='	24	%
P12391	BXGT007811	Neuronal acetylcholine receptor subunit beta-3	reviewed	-	Chrnb3	Enhancement	'='	24	%
Q9JLB5	BXGT020832	Neuronal acetylcholine receptor subunit alpha-10	reviewed	-	Chrna10	Enhancement	'='	24	%
P43144	BXGT010362	Neuronal acetylcholine receptor subunit alpha-9	reviewed	-	Chrna9	Enhancement	'='	24	%
P12392	BXGT007812	Neuronal acetylcholine receptor subunit beta-4	reviewed	-	Chrnb4	Enhancement	'='	24	%
P12390	BXGT007810	Neuronal acetylcholine receptor subunit beta-2	reviewed	-	Chrnb2	Enhancement	'='	24	%
P12389	BXGT007809	Neuronal acetylcholine receptor subunit alpha-2	reviewed	-	Chrna2	Enhancement	'='	24	%
P09483	BXGT006896	Neuronal acetylcholine receptor subunit alpha-4	reviewed	-	Chrna4	Enhancement	'='	24	%
P04757	BXGT006258	Neuronal acetylcholine receptor subunit alpha-3	reviewed	-	Chrna3	Enhancement	'='	24	%
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	ED50	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	ED50	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	ED50	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	ED50	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	ED50	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	ID50	'='	0	mg.kg-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	ID50	'='	0	mg.kg-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	ID50	'='	0	mg.kg-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	ID50	'='	0	mg.kg-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	ID50	'='	0	mg.kg-1
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Kd	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Kd	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Kd	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Kd	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Kd	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kd	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kd	'='	1	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kd	'='	1	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kd	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	1	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	1	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	1	nM
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	Kb	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Selectivity	'='	3	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Selectivity	'='	3	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	Ki	-	-	-
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	Ki	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	Ki	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	IC50	-	-	-
P25025	BXGT009006	C-X-C chemokine receptor type 2	reviewed	G-protein coupled receptor	CXCR2	Ki	-	-	-
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	Ki	-	-	-
P11509	BXGT007716	Cytochrome P450 2A6	reviewed	-	CYP2A6	IC50	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	IC50	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	Ki	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	IC50	'='	3	nM
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	Ki	-	-	-
P08913	BXGT006841	Alpha-2A adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2A	IC50	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kd	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kd	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kd	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kd	'='	0	nM
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	IC50	-	-	-
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	IC50	-	-	-
P50406	BXGT010796	5-hydroxytryptamine receptor 6	reviewed	G-protein coupled receptor	HTR6	IC50	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Selectivity	'='	2	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Selectivity	'='	2	-
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	reviewed	Enzyme	PTPRC	Ki	-	-	-
O70528	BXGT005068	5-hydroxytryptamine receptor 4	reviewed	-	HTR4	Ki	-	-	-
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	IC50	-	-	-
P29476	BXGT009354	Nitric oxide synthase, brain	reviewed	-	Nos1	Ki	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	Ki	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	Ki	-	-	-
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kd	'='	2	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	2	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kd	'='	2	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kd	'='	2	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kd	'='	2	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Kd	'='	1	nM
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	Ki	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kb	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	IC50	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	ED50	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	ED50	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	ED50	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	ED50	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	ED50	'='	0	nM
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	IC50	-	-	-
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	Ki	-	-	-
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	2	-
P21836	BXGT008694	Acetylcholinesterase	reviewed	-	Ache	Ratio	'='	2	-
P21836	BXGT008694	Acetylcholinesterase	reviewed	-	Ache	Ki	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	3	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
Q8WMX0	BXGT018968	Muscarinic receptor M1	unreviewed	-		Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	IC50	'='	1354	nM
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	Ki	-	-	-
P13945	BXGT007972	Beta-3 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB3	Ki	-	-	-
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	Ki	-	-	-
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	Ki	-	-	-
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Ki	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	IC50	-	-	-
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Ki	-	-	-
P03372	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	Ki	-	-	-
Q92731	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	IC50	-	-	-
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	IC50	-	-	-
P32245	BXGT009614	Melanocortin receptor 4	reviewed	G-protein coupled receptor	MC4R	Ki	-	-	-
P30542	BXGT009436	Adenosine receptor A1	reviewed	G-protein coupled receptor	ADORA1	Ki	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	0	nM
P21836	BXGT008694	Acetylcholinesterase	reviewed	-	Ache	Ki	'='	0	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	IC50	-	-	-
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	IC50	-	-	-
P33032	BXGT009689	Melanocortin receptor 5	reviewed	G-protein coupled receptor	MC5R	Ki	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P25929	BXGT009078	Neuropeptide Y receptor type 1	reviewed	G-protein coupled receptor	NPY1R	Ki	-	-	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	1	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	1	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	7	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K 0.5	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K 0.5	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K 0.5	'='	0	nM
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	Inhibition	'='	76	%
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ratio	'='	1	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ratio	'='	1	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	IC50	'='	0	nM
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	IC50	-	-	-
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	IC50	-	-	-
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	IC50	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	-	-	-
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	ED50	'='	0	mg.kg-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	ED50	'='	0	mg.kg-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	ED50	'='	0	mg.kg-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	ED50	'='	0	mg.kg-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	ED50	'='	0	mg.kg-1
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K 0.5	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Kd	'='	2	nM
P43140	BXGT010360	Alpha-1A adrenergic receptor	reviewed	-	Adra1a	IC50	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	1	nM
P47747	BXGT010583	Histamine H2 receptor	reviewed	-	HRH2	K0.5	'='	1236	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	1	nM
Q16539	BXGT013634	Mitogen-activated protein kinase 14	reviewed	Kinase	MAPK14	Ki	-	-	-
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	Ki	-	-	-
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	IC50	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	Ki	'='	530	nM
P24557	BXGT008976	Thromboxane-A synthase	reviewed	-	TBXAS1	IC50	-	-	-
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	Ki	-	-	-
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	IC50	-	-	-
Q690N0	BXGT016199	Progesterone receptor	unreviewed	-	PGR	Ki	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	KA	'='	167000000	M-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	KA	'='	167000000	M-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	KA	'='	167000000	M-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	KA	'='	167000000	M-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	KA	'='	167000000	M-1
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Kd	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Kd	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Kd	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Kd	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Kd	'='	1	nM
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	Ki	-	-	-
P29466	BXGT009349	Caspase-1	reviewed	Enzyme	CASP1	IC50	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	Ki	-	-	-
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	IC50	-	-	-
P25101	BXGT009018	Endothelin-1 receptor	reviewed	G-protein coupled receptor	EDNRA	Ki	-	-	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kb	'='	2	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	ID50	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	ID50	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	ID50	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	ID50	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	ID50	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	%max	'='	1	%
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	135000	nM
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	Ki	-	-	-
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	IC50	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	Ki	-	-	-
P25021	BXGT009004	Histamine H2 receptor	reviewed	G-protein coupled receptor	HRH2	Ki	-	-	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	3	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Selectivity ratio	'='	1	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Selectivity ratio	'='	1	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	K-1	'='	0	min-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	K-1	'='	0	min-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	K-1	'='	0	min-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	K-1	'='	0	min-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	K-1	'='	0	min-1
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	K-2	'='	0	min-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	K-2	'='	0	min-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	K-2	'='	0	min-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	K-2	'='	0	min-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	K-2	'='	0	min-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	IC50	'='	2	nM
P41143	BXGT010223	Delta-type opioid receptor	reviewed	G-protein coupled receptor	OPRD1	Ki	-	-	-
P08246	BXGT006756	Neutrophil elastase	reviewed	Enzyme	ELANE	Ki	-	-	-
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	IC50	-	-	-
P0DMS8	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	Ki	-	-	-
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	Kd	'='	0	nM
P18089	BXGT008379	Alpha-2B adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2B	IC50	-	-	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	Ki	-	-	-
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	IC50	-	-	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	Ki	-	-	-
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	IC50	-	-	-
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	reviewed	Transporter	SLC6A2	IC50	-	-	-
P07943	BXGT006700	Aldo-keto reductase family 1 member B1	reviewed	-	Akr1b1	IC50	-	-	-
P30411	BXGT009424	B2 bradykinin receptor	reviewed	G-protein coupled receptor	BDKRB2	IC50	-	-	-
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	IC50	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Activity	'='	90	%
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	Inhibition	'<'	30	%
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ratio	'='	12	-
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ratio	'='	12	-
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	1	nM
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Analgesic efficacy	'='	42	%
P32211	BXGT009610	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Analgesic efficacy	'='	42	%
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Analgesic efficacy	'='	42	%
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Analgesic efficacy	'='	42	%
Q920H4	BXGT019335	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Analgesic efficacy	'='	42	%
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	K-2	'='	0	min-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	K-2	'='	0	min-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	K-2	'='	0	min-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	K-2	'='	0	min-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	K-2	'='	0	min-1
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	K-1	'='	0	min-1
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	K-1	'='	0	min-1
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	K-1	'='	0	min-1
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	K-1	'='	0	min-1
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	K-1	'='	0	min-1
Q05941	BXGT012847	Neuronal acetylcholine receptor subunit alpha-7	reviewed	-	Chrna7	Mean enhancement of binding	'='	14	-
P20420	BXGT008572	Neuronal acetylcholine receptor subunit alpha-5	reviewed	-	Chrna5	Mean enhancement of binding	'='	14	-
P43143	BXGT010361	Neuronal acetylcholine receptor subunit alpha-6	reviewed	-	Chrna6	Mean enhancement of binding	'='	14	-
P12391	BXGT007811	Neuronal acetylcholine receptor subunit beta-3	reviewed	-	Chrnb3	Mean enhancement of binding	'='	14	-
Q9JLB5	BXGT020832	Neuronal acetylcholine receptor subunit alpha-10	reviewed	-	Chrna10	Mean enhancement of binding	'='	14	-
P43144	BXGT010362	Neuronal acetylcholine receptor subunit alpha-9	reviewed	-	Chrna9	Mean enhancement of binding	'='	14	-
P12392	BXGT007812	Neuronal acetylcholine receptor subunit beta-4	reviewed	-	Chrnb4	Mean enhancement of binding	'='	14	-
P12390	BXGT007810	Neuronal acetylcholine receptor subunit beta-2	reviewed	-	Chrnb2	Mean enhancement of binding	'='	14	-
P12389	BXGT007809	Neuronal acetylcholine receptor subunit alpha-2	reviewed	-	Chrna2	Mean enhancement of binding	'='	14	-
P09483	BXGT006896	Neuronal acetylcholine receptor subunit alpha-4	reviewed	-	Chrna4	Mean enhancement of binding	'='	14	-
P04757	BXGT006258	Neuronal acetylcholine receptor subunit alpha-3	reviewed	-	Chrna3	Mean enhancement of binding	'='	14	-
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	reviewed	Ion channel	SCN3A	Inhibition	'='	4	%
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	reviewed	Ion channel	SCN2A	Inhibition	'='	4	%
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	reviewed	Ion channel	SCN1A	Inhibition	'='	4	%
P21554	BXGT008662	Cannabinoid receptor 1	reviewed	G-protein coupled receptor	CNR1	IC50	-	-	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Selectivity	'='	0	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Selectivity	'='	0	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Kd	'='	0	nM
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	Ki	'>'	20000	nM
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	IC50	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	IC50	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	2	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	2	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	2	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	2	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	2	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Kd	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Kd	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Kd	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Kd	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Kd	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	K app	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	K app	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	K app	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	K app	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	K app	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ratio	'='	3	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ratio	'='	3	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	RBI	'='	3	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	RBI	'='	3	-
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	RBI	'='	3	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	RBI	'='	3	-
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	RBI	'='	3	-
Q9ERZ3	BXGT020311	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	ED50	'='	0	mg.kg-1
P32211	BXGT009610	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	ED50	'='	0	mg.kg-1
P12657	BXGT007831	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	ED50	'='	0	mg.kg-1
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	ED50	'='	0	mg.kg-1
Q920H4	BXGT019335	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	ED50	'='	0	mg.kg-1
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Ki	'='	0	nM
P28482	BXGT009263	Mitogen-activated protein kinase 1	reviewed	Kinase	MAPK1	IC50	-	-	-
P15207	BXGT008096	Androgen receptor	reviewed	-	Ar	Ki	-	-	-
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	reviewed	Kinase	FLT1	IC50	-	-	-
P37288	BXGT009977	Vasopressin V1a receptor	reviewed	G-protein coupled receptor	AVPR1A	Ki	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	Ki	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	0	nM
O15245	BXGT004141	Solute carrier family 22 member 1	reviewed	Transporter	SLC22A1	IC50	'='	12200	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Activity	-	-	-
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	Ki	'='	0	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	Ki	'='	0	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Ki	'='	0	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	Ki	'='	0	nM
Q9ERZ4	BXGT020312	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Ki	'='	0	nM
P35354	BXGT009816	Prostaglandin G/H synthase 2	reviewed	Enzyme	PTGS2	Ki	-	-	-
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	IC50	-	-	-
P35462	BXGT009835	D(3) dopamine receptor	reviewed	G-protein coupled receptor	DRD3	IC50	-	-	-
Q01959	BXGT012624	Sodium-dependent dopamine transporter	reviewed	Transporter	SLC6A3	Ki	-	-	-
P04150	BXGT006154	Glucocorticoid receptor	reviewed	Nuclear receptor	NR3C1	Ki	-	-	-
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	Ki	-	-	-
P04035	BXGT006129	3-hydroxy-3-methylglutaryl-coenzyme A reductase	reviewed	-	HMGCR	Ki	-	-	-
A6XA80	BXGT001522	Leukotriene C4 synthase	reviewed	-	LTC4S	IC50	-	-	-
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	Ki	-	-	-
P25100	BXGT009017	Alpha-1D adrenergic receptor	reviewed	G-protein coupled receptor	ADRA1D	Ki	'='	666	nM
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	IC50	-	-	-
P50052	BXGT010768	Type-2 angiotensin II receptor	reviewed	G-protein coupled receptor	AGTR2	Ki	-	-	-
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	IC50	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	IC50	-	-	-
P51679	BXGT010877	C-C chemokine receptor type 4	reviewed	G-protein coupled receptor	CCR4	IC50	-	-	-
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	IC50	-	-	-
P25024	BXGT009005	C-X-C chemokine receptor type 1	reviewed	G-protein coupled receptor	CXCR1	Ki	-	-	-
P32238	BXGT009611	Cholecystokinin receptor type A	reviewed	G-protein coupled receptor	CCKAR	IC50	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Ki	-	-	-
P05181	BXGT006337	Cytochrome P450 2E1	reviewed	-	CYP2E1	Ki	-	-	-
Q8WMX0	BXGT018968	Muscarinic receptor M1	unreviewed	-		Ki	'='	2	nM
Q8BW75	BXGT017924	Amine oxidase [flavin-containing] B	reviewed	-	Maob	Activity	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kd	'='	0	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kd	'='	0	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kd	'='	0	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kd	'='	0	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	Selectivity ratio	'='	0	-
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	Selectivity ratio	'='	0	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	0	nM
A9XFY4	BXGT001818	Nicotinic acetylcholine receptor alpha 5 subunit	unreviewed	-	nAChRalpha5	Ki	'='	32500	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Ki	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ki	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	Ki	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	Ki	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	Ki	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	Ki	-	-	-
P35367	BXGT009821	Histamine H1 receptor	reviewed	G-protein coupled receptor	HRH1	IC50	-	-	-
Q9Y271	BXGT022222	Cysteinyl leukotriene receptor 1	reviewed	G-protein coupled receptor	CYSLTR1	IC50	-	-	-
Q8VH26	BXGT018927	Muscarinic acetylcholine receptor	unreviewed	-	GPM3	ID50	'='	0	mg.kg-1
P41145	BXGT010225	Kappa-type opioid receptor	reviewed	G-protein coupled receptor	OPRK1	IC50	-	-	-
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Ki	-	-	-
P12822	BXGT007850	Angiotensin-converting enzyme	reviewed	-	ACE	IC50	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Ki	-	-	-
P17252	BXGT008294	Protein kinase C alpha type	reviewed	Kinase	PRKCA	Ki	-	-	-
P19327	BXGT008472	5-hydroxytryptamine receptor 1A	reviewed	-	Htr1a	IC50	-	-	-
P41595	BXGT010267	5-hydroxytryptamine receptor 2B	reviewed	G-protein coupled receptor	HTR2B	IC50	-	-	-
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	reviewed	G-protein coupled receptor	HTR2C	IC50	'='	1012	nM
P31645	BXGT009558	Sodium-dependent serotonin transporter	reviewed	Transporter	SLC6A4	IC50	-	-	-
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	IC50	-	-	-
P21452	BXGT008653	Substance-K receptor	reviewed	G-protein coupled receptor	TACR2	Ki	-	-	-
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Ki	-	-	-
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	IC50	-	-	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	Ki	-	-	-
P18825	BXGT008426	Alpha-2C adrenergic receptor	reviewed	G-protein coupled receptor	ADRA2C	IC50	-	-	-
P30988	BXGT009491	Calcitonin receptor	reviewed	G-protein coupled receptor	CALCR	Ki	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	-	-	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	IC50	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	IC50	-	-	-
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	IC50	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	Ki	-	-	-
P15127	BXGT008085	Insulin receptor	reviewed	-	Insr	Ki	-	-	-
P12530	BXGT007827	Arachidonate 15-lipoxygenase	reviewed	-	ALOX15	Ki	-	-	-
P41968	BXGT010275	Melanocortin receptor 3	reviewed	G-protein coupled receptor	MC3R	Ki	-	-	-
P21397	BXGT008644	Amine oxidase [flavin-containing] A	reviewed	-	MAOA	IC50	-	-	-
P15823	BXGT008160	Alpha-1B adrenergic receptor	reviewed	-	Adra1b	IC50	-	-	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	IC50	-	-	-
P41597	BXGT010268	C-C chemokine receptor type 2	reviewed	-	CCR2	Ki	-	-	-
P51681	BXGT010878	C-C chemokine receptor type 5	reviewed	G-protein coupled receptor	CCR5	Ki	-	-	-
P23219	BXGT008837	Prostaglandin G/H synthase 1	reviewed	Enzyme	PTGS1	Ki	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	IC50	-	-	-
P21917	BXGT008707	D(4) dopamine receptor	reviewed	G-protein coupled receptor	DRD4	IC50	-	-	-
P20781	BXGT008598	Glycine receptor subunit beta	reviewed	-	Glrb	IC50	-	-	-
P07727	BXGT006662	Glycine receptor subunit alpha-1	reviewed	-	Glra1	IC50	-	-	-
P24524	BXGT008974	Glycine receptor subunit alpha-3	reviewed	-	Glra3	IC50	-	-	-
P22771	BXGT008806	Glycine receptor subunit alpha-2	reviewed	-	Glra2	IC50	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	IC50	-	-	-
P29274	BXGT009327	Adenosine receptor A2a	reviewed	G-protein coupled receptor	ADORA2A	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Kd	'='	1	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Kd	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Kd	'='	1	nM
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Kd	'='	1	nM
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	reviewed	G-protein coupled receptor	CHRM3	Kd	'='	1	nM
P10980	BXGT007641	Muscarinic acetylcholine receptor M2	reviewed	-	Chrm2	IC50	'='	1	nM
P08911	BXGT006839	Muscarinic acetylcholine receptor M5	reviewed	-	Chrm5	IC50	'='	1	nM
P08485	BXGT006777	Muscarinic acetylcholine receptor M4	reviewed	-	Chrm4	IC50	'='	1	nM
P08483	BXGT006776	Muscarinic acetylcholine receptor M3	reviewed	-	Chrm3	IC50	'='	1	nM
P08482	BXGT006775	Muscarinic acetylcholine receptor M1	reviewed	-	Chrm1	IC50	'='	1	nM
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Ki	'='	1	nM
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	reviewed	-	PPP3CA	IC50	-	-	-
P25103	BXGT009020	Substance-P receptor	reviewed	G-protein coupled receptor	TACR1	Ki	-	-	-
P08173	BXGT006738	Muscarinic acetylcholine receptor M4	reviewed	G-protein coupled receptor	CHRM4	Ki	'='	1	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	0	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	2	nM
P11229	BXGT007676	Muscarinic acetylcholine receptor M1	reviewed	G-protein coupled receptor	CHRM1	Ki	'='	1	nM
P06241	BXGT006429	Tyrosine-protein kinase Fyn	reviewed	Kinase	FYN	Ki	-	-	-
P08912	BXGT006840	Muscarinic acetylcholine receptor M5	reviewed	G-protein coupled receptor	CHRM5	Inhibition	-	-	-
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	1000000	nM
P08172	BXGT006737	Muscarinic acetylcholine receptor M2	reviewed	G-protein coupled receptor	CHRM2	Ki	'='	1	nM
P49146	BXGT010681	Neuropeptide Y receptor type 2	reviewed	G-protein coupled receptor	NPY2R	IC50	-	-	-
P08311	BXGT006762	Cathepsin G	reviewed	Enzyme	CTSG	IC50	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05659	Datura stramonium	Datura stramonium	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}