Showing entry for Transcobalamin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008542
Protein NameTranscobalamin-1
Uniport IdP20061
GeneTCN1
Gene Id6947
DomainCobalamin_bind; DUF4430
Pfam PF01122   PF14478  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009235 cobalamin metabolic process
Biological Process GO:0015889 cobalamin transport
Biological Process GO:0006824 cobalt ion transport
Biological Process GO:0043312 neutrophil degranulation
molecular function GO:0031419 cobalamin binding
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0035580 specific granule lumen
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0002888 BXGD000145 Anemia, Megaloblastic Hemic and Lymphatic Diseases
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0021125 BXGD001483 Impulsive Behavior Behavior and Behavior Mechanisms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0029121 BXGD002112 Oppositional Defiant Disorder Mental Disorders
C0042847 BXGD003006 Vitamin B 12 Deficiency Nutritional and Metabolic Diseases
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0202252 BXGD004089 VITAMIN B12 MEASUREMENT
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0275524 BXGD006376 Coinfection Infections
C0280321 BXGD006739 Squamous cell carcinoma of the hypopharynx
C0342700 BXGD007528 Transcobalamin I Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0342701 BXGD007529 Transcobalamin II deficiency
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349208 BXGD007893 Manic episode Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1842981 BXGD014547 NEUROTICISM Behavior and Behavior Mechanisms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3665444 BXGD019288 Neutrophilia (disorder) Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003751 Cyanide 26.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein