Showing entry for Azurocidin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008548
Protein NameAzurocidin
Uniport IdP20160
GeneAZU1
Gene Id566
DomainTrypsin
Pfam PF00089  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019730 antimicrobial humoral response
Biological Process GO:0035584 calcium-mediated signaling using intracellular calcium source
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:0045123 cellular extravasation
Biological Process GO:0050829 defense response to Gram-negative bacterium
Biological Process GO:0051607 defense response to virus
Biological Process GO:0032603 fractalkine production
Biological Process GO:0008347 glial cell migration
Biological Process GO:0050930 induction of positive chemotaxis
Biological Process GO:0006954 inflammatory response
Biological Process GO:0048246 macrophage chemotaxis
Biological Process GO:0001774 microglial cell activation
Biological Process GO:0042117 monocyte activation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0070944 neutrophil-mediated killing of bacterium
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0032731 positive regulation of interleukin-1 beta production
Biological Process GO:0045348 positive regulation of MHC class II biosynthetic process
Biological Process GO:0010800 positive regulation of peptidyl-threonine phosphorylation
Biological Process GO:0050766 positive regulation of phagocytosis
Biological Process GO:0045860 positive regulation of protein kinase activity
Biological Process GO:0042535 positive regulation of tumor necrosis factor biosynthetic process
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0070528 protein kinase C signaling
Biological Process GO:0006508 proteolysis
Biological Process GO:0043114 regulation of vascular permeability
molecular function GO:0043395 heparan sulfate proteoglycan binding
molecular function GO:0008201 heparin binding
molecular function GO:0008233 peptidase activity
molecular function GO:0004252 serine-type endopeptidase activity
molecular function GO:0015643 toxic substance binding
cellular component GO:0042582 azurophil granule
cellular component GO:0035578 azurophil granule lumen
cellular component GO:0035577 azurophil granule membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0019898 extrinsic component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000833 BXGD000014 Abscess Pathological Conditions, Signs and Symptoms; Infections
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023211 BXGD001615 Left Bundle-Branch Block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0023364 BXGD001638 Leptospirosis Infections
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030286 BXGD002201 Pancreatic Diseases Digestive System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0041834 BXGD002935 Erythema Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C0042029 BXGD002951 Urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085437 BXGD003178 Meningitis, Bacterial Infections; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206669 BXGD004229 Hepatocellular Adenoma Digestive System Diseases; Neoplasms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0265025 BXGD005450 Capillary hyperpermeability
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0267878 BXGD005787 Mirizzi Syndrome Digestive System Diseases
C0275524 BXGD006376 Coinfection Infections
C0275551 BXGD006379 Primary bacterial peritonitis Digestive System Diseases; Infections
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0334121 BXGD006996 Inflammatory Myofibroblastic Tumor Pathological Conditions, Signs and Symptoms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0406317 BXGD008334 Chronic small plaque psoriasis Skin and Connective Tissue Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1536220 BXGD013341 ST segment elevation myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1719672 BXGD013659 Severe Sepsis Pathological Conditions, Signs and Symptoms; Infections
C1842981 BXGD014547 NEUROTICISM Behavior and Behavior Mechanisms
C2004489 BXGD016873 Regurgitation
C2062441 BXGD016897 Influenza A
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C3825986 BXGD019709 Meningitis in children
C4699152 BXGD023634 ST-segment elevation myocardial infarction (STEMI)
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000434 Ethanol 46.07
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein