Showing entry for D(2) dopamine receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008560
Protein NameD(2) dopamine receptor
Uniport IdP20288
GeneDRD2
Gene Id281126
Domain7tm_1
Pfam PF00001  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:1990384 hyaloid vascular plexus regression
Biological Process GO:0007194 negative regulation of adenylate cyclase activity
Biological Process GO:0051481 negative regulation of cytosolic calcium ion concentration
Biological Process GO:1903488 negative regulation of lactation
Biological Process GO:1902721 negative regulation of prolactin secretion
Biological Process GO:0051967 negative regulation of synaptic transmission, glutamatergic
Biological Process GO:1901386 negative regulation of voltage-gated calcium channel activity
Biological Process GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:1903521 positive regulation of mammary gland involution
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:0043266 regulation of potassium ion transport
Biological Process GO:0001963 synaptic transmission, dopaminergic
molecular function GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go
molecular function GO:0004930 G protein-coupled receptor activity
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0000139 Golgi membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0004548 4-(beta-Methylaminoethyl)catechol 167.21
BXGC0005871 Dopamine 153.18
BXGC0014322 (S)-Bulbocapnine 325.13
BXGC0042222 Propranolol 259.16
BXGC0045812 Trifluoperazine 407.16
BXGC0049061 Pentazocine 285.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein