Showing entry for 5-hydroxytryptamine receptor 1E


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009274
Protein Name5-hydroxytryptamine receptor 1E
Uniport IdP28566
GeneHTR1E
Gene Id3354
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.6 Nervous system hsa04726 Serotonergic synapse
5. Organismal Systems 5.7 Sensory system hsa04742 Taste transduction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375280 Amine ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-390666 Serotonin receptors
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0017638 BXGD001132 Glioma Neoplasms
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0856169 BXGD011096 Endothelial dysfunction
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1266129 BXGD011970 Atypical Lipoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000548 Tryptamine 160.22
BXGC0003196 Aripiprazole 448.39
BXGC0005867 Serotonin 176.22
BXGC0017369 N-Methyllaurotetanine 341.16
BXGC0040582 nantenine 339.15
BXGC0043578 5-Hydroxy-2-(2-Phenylethyl)Chromen-4-One 266.09
BXGC0046755 Yohimbine 354.19
BXGC0052798 5-Meo-Dmt 218.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein