Showing entry for Metabotropic glutamate receptor 4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009541
Protein NameMetabotropic glutamate receptor 4
Uniport IdP31423
GeneGrm4
Gene Id24417
Domain7tm_3; ANF_receptor; NCD3G
Pfam PF00003   PF01094   PF07562  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0014051 gamma-aminobutyric acid secretion
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007612 learning
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0050805 negative regulation of synaptic transmission
Biological Process GO:0031175 neuron projection development
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0043523 regulation of neuron apoptotic process
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0051932 synaptic transmission, GABAergic
Biological Process GO:0035249 synaptic transmission, glutamatergic
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0008066 glutamate receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0001642 group III metabotropic glutamate receptor activity
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0043198 dendritic shaft
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099059 integral component of presynaptic active zone membrane
cellular component GO:0043005 neuron projection
cellular component GO:0098688 parallel fiber to Purkinje cell synapse
cellular component GO:0048787 presynaptic active zone membrane
cellular component GO:0043195 terminal bouton
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000651 Harmalan 184.24
BXGC0001545 Harmine 212.25
BXGC0001642 Tricholomic acid 160.13
BXGC0006162 L-Glutamic acid 147.13
BXGC0023948 (S)-2-Aminoadipic Acid 161.07
BXGC0036441 Quisqualate 189.04
BXGC0036476 D-Glutamate 147.05
BXGC0046860 4-methylene-D-glutamic acid 159.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein