Showing entry for Tyrosine-protein phosphatase non-receptor type 7


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009802
Protein NameTyrosine-protein phosphatase non-receptor type 7
Uniport IdP35236
GenePTPN7
Gene Id5778
DomainY_phosphatase
Pfam PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0006470 protein dephosphorylation
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0009898 cytoplasmic side of plasma membrane
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-446652 Interleukin-1 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5675221 Negative regulation of MAPK pathway
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-9008059 Interleukin-37 signaling
R-HSA-9607240 FLT3 Signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085702 BXGD003247 Monocytosis Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0206687 BXGD004242 Carcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376544 BXGD008001 Hematopoietic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1569637 BXGD013424 Adenocarcinoma, Endometrioid Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000076 p-Coumaroyl tartaric acid glucosidic ester 150.09
BXGC0000436 Glycerol 92.09
BXGC0000696 Tartaric acid 150.09
BXGC0001857 Caffeic acid 180.16
BXGC0003627 alpha-Linoleic acid 280.45
BXGC0003705 Chloride 35.45
BXGC0004965 Rhein 284.22
BXGC0006326 Imperatorin 270.28
BXGC0006466 Oleanolic acid 456.71
BXGC0011627 Glycyrrhetic acid 470.69
BXGC0014048 Celastrol 450.28
BXGC0015288 mesotartaric acid 150.02
BXGC0020328 stigmasterol glucoside 574.42
BXGC0020344 Icosa-5,8,11,14-Tetraynoic Acid 296.18
BXGC0020680 Mandelic Acid 152.05
BXGC0022865 (2S)-2-Hydroxy-2-Phenylacetic Acid 152.05
BXGC0027720 (r)-mandelic acid 152.05
BXGC0029191 5-hydroxy-2-hydroxymethylpyridine 125.05
BXGC0042410 10Z,13Z-Nonadecadienoic Acid 294.26
BXGC0049247 dotriacontanoic acid 480.49
BXGC0052172 12-octadecenoic acid 282.26
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein