Showing entry for Alcohol dehydrogenase class 4 mu/sigma chain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010178
Protein NameAlcohol dehydrogenase class 4 mu/sigma chain
Uniport IdP40394
GeneADH7
Gene Id131
DomainADH_N; ADH_zinc_N
Pfam PF08240   PF00107  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.1 Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis
1. Metabolism 1.3 Lipid metabolism hsa00071 Fatty acid degradation
1. Metabolism 1.5 Amino acid metabolism hsa00350 Tyrosine metabolism
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00830 Retinol metabolism
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450
1. Metabolism 1.11 Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006068 ethanol catabolic process
Biological Process GO:0006069 ethanol oxidation
Biological Process GO:0010430 fatty acid omega-oxidation
Biological Process GO:0055114 oxidation-reduction process
Biological Process GO:0009617 response to bacterium
Biological Process GO:0045471 response to ethanol
Biological Process GO:0042573 retinoic acid metabolic process
Biological Process GO:0001523 retinoid metabolic process
Biological Process GO:0042572 retinol metabolic process
molecular function GO:0004022 alcohol dehydrogenase (NAD+) activity
molecular function GO:0004024 alcohol dehydrogenase activity, zinc-dependent
molecular function GO:0004031 aldehyde oxidase activity
molecular function GO:0035276 ethanol binding
molecular function GO:0050153 omega-hydroxydecanoate dehydrogenase activity
molecular function GO:0048019 receptor antagonist activity
molecular function GO:0019841 retinol binding
molecular function GO:0004745 retinol dehydrogenase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-211859 Biological oxidations
R-HSA-211945 Phase I - Functionalization of compounds
R-HSA-71384 Ethanol oxidation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003076 BXGD000171 Aniridia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0018671 BXGD001211 Head and Neck Neoplasms Neoplasms
C0023055 BXGD001604 Laryngeal neoplasm Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0026640 BXGD001912 Mouth Neoplasms Neoplasms; Stomatognathic Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028043 BXGD002066 Nicotine Dependence Chemically-Induced Disorders; Mental Disorders
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031347 BXGD002299 Pharyngeal Neoplasms Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038580 BXGD002771 Substance Dependence Chemically-Induced Disorders; Mental Disorders
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153405 BXGD003632 Malignant neoplasm of pharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0271183 BXGD006169 Severe myopia Eye Diseases
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0339527 BXGD007260 Leber Congenital Amaurosis Eye Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751688 BXGD010551 Malignant Squamous Cell Neoplasm Neoplasms
C0854723 BXGD011026 Retinal Dystrophies Eye Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722419 BXGD023802 Extrapulmonary Small Cell Carcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0018736 Benzamide 121.05
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein