Showing entry for Centrin-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010233
Protein NameCentrin-2
Uniport IdP41208
GeneCETN2
Gene Id1069
DomainEF-hand_7
Pfam PF13499  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.4 Replication and repair hsa03420 Nucleotide excision repair
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0007099 centriole replication
Biological Process GO:0097711 ciliary basal body-plasma membrane docking
Biological Process GO:0000086 G2/M transition of mitotic cell cycle
Biological Process GO:0070911 global genome nucleotide-excision repair
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0051028 mRNA transport
Biological Process GO:0006289 nucleotide-excision repair
Biological Process GO:0000715 nucleotide-excision repair, DNA damage recognition
Biological Process GO:0000717 nucleotide-excision repair, DNA duplex unwinding
Biological Process GO:0006294 nucleotide-excision repair, preincision complex assembly
Biological Process GO:0015031 protein transport
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0010389 regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0007283 spermatogenesis
molecular function GO:0005509 calcium ion binding
molecular function GO:0031683 G-protein beta/gamma-subunit complex binding
molecular function GO:0032795 heterotrimeric G-protein binding
molecular function GO:0008017 microtubule binding
cellular component GO:0097729 9+2 motile cilium
cellular component GO:0045177 apical part of cell
cellular component GO:0005814 centriole
cellular component GO:0005813 centrosome
cellular component GO:0036064 ciliary basal body
cellular component GO:0005829 cytosol
cellular component GO:0005622 intracellular
cellular component GO:0044615 nuclear pore nuclear basket
cellular component GO:0005654 nucleoplasm
cellular component GO:0032391 photoreceptor connecting cilium
cellular component GO:0070390 transcription export complex 2
cellular component GO:0071942 XPC complex
Reactome
Pathway Id Pathway Name
R-HSA-1640170 Cell Cycle
R-HSA-1852241 Organelle biogenesis and maintenance
R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition
R-HSA-2990846 SUMOylation
R-HSA-3108214 SUMOylation of DNA damage response and repair proteins
R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
R-HSA-380259 Loss of Nlp from mitotic centrosomes
R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes
R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome
R-HSA-380287 Centrosome maturation
R-HSA-380320 Recruitment of NuMA to mitotic centrosomes
R-HSA-392499 Metabolism of proteins
R-HSA-453274 Mitotic G2-G2/M phases
R-HSA-5617833 Cilium Assembly
R-HSA-5620912 Anchoring of the basal body to the plasma membrane
R-HSA-5696394 DNA Damage Recognition in GG-NER
R-HSA-5696395 Formation of Incision Complex in GG-NER
R-HSA-5696398 Nucleotide Excision Repair
R-HSA-5696399 Global Genome Nucleotide Excision Repair (GG-NER)
R-HSA-597592 Post-translational protein modification
R-HSA-68877 Mitotic Prometaphase
R-HSA-68886 M Phase
R-HSA-69275 G2/M Transition
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-73894 DNA Repair
R-HSA-8854518 AURKA Activation by TPX2
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004114 BXGD000255 Astrocytoma Neoplasms
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0021364 BXGD001500 Male infertility Male Urogenital Diseases
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0235287 BXGD004738 Dysosmia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278488 BXGD006515 Carcinoma breast stage IV
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1328840 BXGD012474 Autoimmune Lymphoproliferative Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C2752147 BXGD017769 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3888024 BXGD019943 Cacosmia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4277690 BXGD022377 Ciliopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein