adisease

Showing entry for Adult Meningioma

General Disease Information
BXGD Id	BXGD006608
Disease Name	Adult Meningioma
Disease CUI Id	C0278877
MeSH Codes	C04 C10
Disease Class Name	Neoplasms; Nervous System Diseases
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	6446	reviewed	Kinase
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00255	BXGT003903	Menin	4221	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O15297	BXGT004149	Protein phosphatase 1D	8493	reviewed	Enzyme
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O43324	BXGT004588	Eukaryotic translation elongation factor 1 epsilon-1	9521	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75473	BXGT005129	Leucine-rich repeat-containing G-protein coupled receptor 5	8549	reviewed	G-protein coupled receptor
O95271	BXGT005369	Poly [ADP-ribose] polymerase tankyrase-1	8658	reviewed
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	11200	reviewed	Kinase
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01148	BXGT005739	Progonadoliberin-1	2796	reviewed
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02144	BXGT005853	Myoglobin	4151	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03950	BXGT006116	Angiogenin	283	reviewed
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06493	BXGT006445	Cyclin-dependent kinase 1	983	reviewed	Kinase
P06576	BXGT006454	ATP synthase subunit beta, mitochondrial	506	reviewed	Transporter
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07437	BXGT006624	Tubulin beta chain	203068	reviewed	Cellular structure
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08574	BXGT006792	Cytochrome c1, heme protein, mitochondrial	1537	reviewed
P08670	BXGT006810	Vimentin	7431	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11388	BXGT007697	DNA topoisomerase 2-alpha	7153	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12830	BXGT007852	Cadherin-1	999	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14635	BXGT008031	G2/mitotic-specific cyclin-B1	891	reviewed	Enzyme modulator
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15085	BXGT008077	Carboxypeptidase A1	1357	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P16471	BXGT008233	Prolactin receptor	5618	reviewed	Signaling
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20062	BXGT008543	Transcobalamin-2	6948	reviewed
P21266	BXGT008632	Glutathione S-transferase Mu 3	2947	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21709	BXGT008685	Ephrin type-A receptor 1	2041	reviewed	Kinase
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P23528	BXGT008879	Cofilin-1	1072	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27540	BXGT009190	Aryl hydrocarbon receptor nuclear translocator	405	reviewed	Transcription factor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30405	BXGT009423	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	10105	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35408	BXGT009828	Prostaglandin E2 receptor EP4 subtype	5734	reviewed	G-protein coupled receptor
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37802	BXGT010013	Transgelin-2	8407	reviewed	Cellular structure
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41208	BXGT010233	Centrin-2	1069	reviewed	Calcium-binding protein
P41212	BXGT010235	Transcription factor ETV6	2120	reviewed	Transcription factor
P41222	BXGT010237	Prostaglandin-H2 D-isomerase	5730	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47895	BXGT010593	Aldehyde dehydrogenase family 1 member A3	220	reviewed	Enzyme
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P51668	BXGT010875	Ubiquitin-conjugating enzyme E2 D1	7321	reviewed	Enzyme
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P52732	BXGT010948	Kinesin-like protein KIF11	3832	reviewed	Cellular structure
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P58004	BXGT011222	Sestrin-2	83667	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60842	BXGT011330	Eukaryotic initiation factor 4A-I	1973	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62993	BXGT011480	Growth factor receptor-bound protein 2	2885	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63010	BXGT011484	AP-2 complex subunit beta	163	reviewed	Transporter
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P63279	BXGT011514	SUMO-conjugating enzyme UBC9	7329	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78358	BXGT011838	Cancer/testis antigen 1	246100	reviewed
Q00613	BXGT012540	Heat shock factor protein 1	3297	reviewed	Transcription factor
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q01523	BXGT012594	Defensin-5	1670	reviewed
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q03405	BXGT012713	Urokinase plasminogen activator surface receptor	5329	reviewed
Q04637	BXGT012771	Eukaryotic translation initiation factor 4 gamma 1	1981	reviewed	Nucleic acid binding
Q05397	BXGT012815	Focal adhesion kinase 1	5747	reviewed	Kinase
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q07157	BXGT012920	Tight junction protein ZO-1	7082	reviewed	Cell-cell junction
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q08050	BXGT012958	Forkhead box protein M1	2305	reviewed
Q12913	BXGT013279	Receptor-type tyrosine-protein phosphatase eta	5795	reviewed	Enzyme
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q14191	BXGT013452	Werner syndrome ATP-dependent helicase	7486	reviewed	Enzyme
Q14240	BXGT013458	Eukaryotic initiation factor 4A-II	1974	reviewed
Q14469	BXGT013473	Transcription factor HES-1	3280	reviewed	Transcription factor
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15257	BXGT013554	Serine/threonine-protein phosphatase 2A activator	5524	reviewed	Enzyme modulator
Q15392	BXGT013566	Delta(24)-sterol reductase	1718	reviewed	Enzyme
Q15717	BXGT013589	ELAV-like protein 1	1994	reviewed
Q16658	BXGT013651	Fascin	6624	reviewed	Cellular structure
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q16881	BXGT013688	Thioredoxin reductase 1, cytoplasmic	7296	reviewed	Enzyme
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6ZQW0	BXGT016635	Indoleamine 2,3-dioxygenase 2	169355	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q7Z3E1	BXGT017250	Protein mono-ADP-ribosyltransferase TIPARP	25976	reviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TD19	BXGT018804	Serine/threonine-protein kinase Nek9	91754	reviewed	Kinase
Q8TEK3	BXGT018822	Histone-lysine N-methyltransferase, H3 lysine-79 specific	84444	reviewed	Epigenetic regulator
Q969G3	BXGT019607	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	6605	reviewed
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q96JY6	BXGT019684	PDZ and LIM domain protein 2	64236	reviewed	Cellular structure
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q99835	BXGT019969	Smoothened homolog	6608	reviewed	G-protein coupled receptor
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9NR28	BXGT021178	Diablo homolog, mitochondrial	56616	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UIF7	BXGT021717	Adenine DNA glycosylase	4595	reviewed	Enzyme
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9UN36	BXGT021780	Protein NDRG2	57447	reviewed	Enzyme
Q9Y2W7	BXGT022250	Calsenilin	30818	reviewed	Ion channel
Q9Y3S1	BXGT022266	Serine/threonine-protein kinase WNK2	65268	reviewed	Kinase
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q13029	BXGT022688	PR domain zinc finger protein 2	7799	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P23497	BXGT024062	Nuclear autoantigen Sp-100	6672	reviewed
P21926	BXGT024578	CD9 antigen	928	reviewed
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P98082	BXGT025047	Disabled homolog 2	1601	reviewed	Signaling
Q5BJF2	BXGT026107	Sigma intracellular receptor 2	27346	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
Q08477	BXGT026164	Docosahexaenoic acid omega-hydroxylase CYP4F3	4051	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}