acompound

Showing entry for Kainic Acid

General Compound Information
BXGC Id	BXGC0049516
Compound Name	Kainic Acid
Structure
Formula	C10H15NO4
InchiKey	VLSMHEGGTFMBBZ-OOZYFLPDSA-N
SMILES	OC(=O)C[C@H]1[C@H](CN[C@@H]1C(=O)O)C(=C)C
Inchi	InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
IUPAC	(2S,3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-ylpyrrolidin-1-ium-2-carboxylate
Molecular Weight	213.1
Pubchem Id	10255
Chembl Id	CHEMBL275040

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

KAI

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P19491	BXGT008489	Glutamate receptor 2	reviewed	Gria2	-	-	14500	-	-
P19491	BXGT008489	Glutamate receptor 2	reviewed	Gria2	-	-	-	-	-
P19491	BXGT008489	Glutamate receptor 2	reviewed	Gria2	-	-	-	160	-
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	Grik2	-	64.6	-	-	-
P19491	BXGT008489	Glutamate receptor 2	reviewed	Gria2	-	624	-	-	-
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	Grik2	-	-	-	-	-
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	Grik1	-	-	-	-	-
P19493	BXGT008491	Glutamate receptor 4	reviewed	Gria4	-	-	-	-	-
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	Grik3	-	-	-	-	-
P19492	BXGT008490	Glutamate receptor 3	reviewed	Gria3	-	30260	-	-	-
P19492	BXGT008490	Glutamate receptor 3	reviewed	Gria3	-	2080	-	-	-
P19492	BXGT008490	Glutamate receptor 3	reviewed	Gria3	-	3440	-	-	-
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	Grik4	-	-	-	1.9	-

Binding DB

50002369

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT013620	Glutamate receptor ionotropic, kainate 4	reviewed	Ion channel	GRIK4	2.29	-	-	-
reviewed	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed		Grik1	2.2	-	-	-
reviewed	BXGT010295	Glutamate receptor 3	reviewed	Ion channel	GRIA3	2630	-	-	-
reviewed	BXGT010295	Glutamate receptor 3	reviewed	Ion channel	GRIA3	8050	-	-	-
reviewed	BXGT008490	Glutamate receptor 3	reviewed		Gria3	5780	-	-	-
reviewed	BXGT008490	Glutamate receptor 3	reviewed		Gria3	1.8	-	-	-
reviewed	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	32	-	-	-
reviewed	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed		Grin1	-	>100000	-	-
reviewed	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed		Grik2	3.7	-	-	-
reviewed	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	53	-	-	-
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	7449	-	-	-
reviewed	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	12221	-	-	-
reviewed	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	8	-	-	-
reviewed	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	-	-	-	700
reviewed	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	177	-	-	-
reviewed	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	-	-	-	16200
reviewed	BXGT013304	Glutamate receptor ionotropic, kainate 3	reviewed	Ion channel	GRIK3	10	-	-	-
reviewed	BXGT010614	Glutamate receptor 4	reviewed	Ion channel	GRIA4	1714	-	-	-
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	-	-	-	7510
reviewed	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	-	-	-	10570
reviewed	BXGT010295	Glutamate receptor 3	reviewed	Ion channel	GRIA3	-	-	-	26610
reviewed	BXGT008488	Glutamate receptor 1	reviewed		Gria1	-	-	-	27000
reviewed	BXGT008490	Glutamate receptor 3	reviewed		Gria3	-	-	-	31000
reviewed	BXGT008488	Glutamate receptor 1	reviewed		Gria1	-	-	-	23000
reviewed	BXGT008489	Glutamate receptor 2	reviewed		Gria2	-	-	-	380000
reviewed	BXGT008490	Glutamate receptor 3	reviewed		Gria3	-	-	-	40000
reviewed	BXGT008491	Glutamate receptor 4	reviewed		Gria4	-	-	-	47000
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	-	-	-	73000
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	-	-	-	60000
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	7500	-	-	-
reviewed	BXGT010614	Glutamate receptor 4	reviewed	Ion channel	GRIA4	1710	-	-	-
reviewed	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed		Grik1	-	-	-	12000
reviewed	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	12200	-	-	-
reviewed	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	80	-	-	-
reviewed	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	7450	-	-	-
reviewed	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	177	-	-	-
reviewed	BXGT007506	Adenosine receptor A3	reviewed	G-protein coupled receptor	ADORA3	-	77	-	-
reviewed	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed		Grik2	-	-	39	-
reviewed	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed		Grik2	12.7	-	-	-
reviewed	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed		Grik3	32.8	-	-	-
reviewed	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed		Grik4	4.7	-	-	-
reviewed	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed		Grik5	15	-	-	-
reviewed	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed		Grik1	75.9	-	-	-
reviewed	BXGT008488	Glutamate receptor 1	reviewed		Gria1	477	-	-	-
reviewed	BXGT008489	Glutamate receptor 2	reviewed		Gria2	3690	-	-	-
reviewed	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed		Grik1	76	-	-	-
reviewed	BXGT008490	Glutamate receptor 3	reviewed		Gria3	1980	-	-	-
reviewed	BXGT008491	Glutamate receptor 4	reviewed		Gria4	3570	-	-	-
reviewed	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed		Grik1	-	-	-	37000
reviewed	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed		Grik2	-	-	-	1800
reviewed	BXGT010266	Metabotropic glutamate receptor 5	reviewed	G-protein coupled receptor	GRM5	-	-	-	33600
reviewed	BXGT004150	Metabotropic glutamate receptor 6	reviewed	G-protein coupled receptor	GRM6	-	-	-	299000
reviewed	BXGT008489	Glutamate receptor 2	reviewed		Gria2	6300	-	-	-

CHEMBL

CHEMBL275040

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P31596	BXGT009553	Excitatory amino acid transporter 2	reviewed	-	Slc1a2	Control	-	-	-
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	Ki	'='	3	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	EC50	'='	40000	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	EC50	'='	57500	nM
P42262	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	EC50	'='	57500	nM
P42262	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	EC50	'='	10570	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	EC50	'='	73000	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	103	%
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	11220	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	EC50	'='	700	nM
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	Ki	'='	177	nM
Q13003	BXGT013304	Glutamate receptor ionotropic, kainate 3	reviewed	Ion channel	GRIK3	Ki	'='	10	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	5	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	5	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	5	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	5	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	5	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	21136	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	IC50	'='	4000	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	IC50	'='	4000	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	IC50	'='	4000	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	IC50	'='	4000	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Ki	'='	32	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	EC50	'='	7510	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	EC50	'='	23000	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Activity	'='	98	%
Q92830	BXGT019379	Histone acetyltransferase KAT2A	reviewed	-	KAT2A	Potency	-	31622	nM
Q9R1M7	BXGT021417	Glutamate receptor ionotropic, NMDA 3A	reviewed	-	Grin3a	IC50	'>'	100000	nM
Q8VHN2	BXGT018931	Glutamate receptor ionotropic, NMDA 3B	reviewed	-	Grin3b	IC50	'>'	100000	nM
Q62645	BXGT016035	Glutamate receptor ionotropic, NMDA 2D	reviewed	-	Grin2d	IC50	'>'	100000	nM
Q00961	BXGT012556	Glutamate receptor ionotropic, NMDA 2C	reviewed	-	Grin2c	IC50	'>'	100000	nM
Q00960	BXGT012555	Glutamate receptor ionotropic, NMDA 2B	reviewed	-	Grin2b	IC50	'>'	100000	nM
Q00959	BXGT012554	Glutamate receptor ionotropic, NMDA 2A	reviewed	-	Grin2a	IC50	'>'	100000	nM
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	IC50	'>'	100000	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Ki	'='	75	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Rmax	'='	100	%
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	Ki	'='	7449	nM
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	Rmax	'='	100	%
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	19952	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Ki	'='	53	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Response	'='	39	%
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Response	'='	85	%
P41594	BXGT010266	Metabotropic glutamate receptor 5	reviewed	G-protein coupled receptor	GRM5	EC50	'='	33600	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	15848	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Ki	'='	70	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	Relative potency	'='	9	-
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	Relative potency	'='	9	-
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Relative potency	'='	9	-
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	Relative potency	'='	9	-
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Relative potency	'='	9	-
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Response	'='	101	%
Q16478	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	Ki	'='	8	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	12589	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	EC50	'='	380000	nM
O75164	BXGT005104	Lysine-specific demethylase 4A	reviewed	-	KDM4A	Potency	-	39810	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	7	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	7	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	7	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	7	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	7	nM
Q9F4F7	BXGT020344	4'-phosphopantetheinyl transferase ffp	reviewed	-	ffp	Potency	'='	39810	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	EC50	'='	37000	nM
P42263	BXGT010295	Glutamate receptor 3	reviewed	Ion channel	GRIA3	EC50	'='	26610	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	Ki	'='	29	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	Ki	'='	29	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	Ki	'='	29	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	Ki	'='	29	nM
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	39810	nM
Q9R1M7	BXGT021417	Glutamate receptor ionotropic, NMDA 3A	reviewed	-	Grin3a	Ki	'>'	100000	nM
Q8VHN2	BXGT018931	Glutamate receptor ionotropic, NMDA 3B	reviewed	-	Grin3b	Ki	'>'	100000	nM
Q62645	BXGT016035	Glutamate receptor ionotropic, NMDA 2D	reviewed	-	Grin2d	Ki	'>'	100000	nM
Q00961	BXGT012556	Glutamate receptor ionotropic, NMDA 2C	reviewed	-	Grin2c	Ki	'>'	100000	nM
Q00960	BXGT012555	Glutamate receptor ionotropic, NMDA 2B	reviewed	-	Grin2b	Ki	'>'	100000	nM
Q00959	BXGT012554	Glutamate receptor ionotropic, NMDA 2A	reviewed	-	Grin2a	Ki	'>'	100000	nM
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	Ki	'>'	100000	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	Ki	'='	32	nM
O15648	BXGT004185	ATP-dependent 6-phosphofructokinase	reviewed	-	pfk	Potency	-	33807	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Kd	'='	39	nM
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	IC50	'>'	100000	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	11	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	11	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	11	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	11	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	11	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	EC50	'='	60000	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	EC50	'='	31000	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	20	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	20	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	20	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	20	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	20	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	Ki	'='	3570	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	16	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	16	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	16	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	16	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	16	nM
Q13003	BXGT013304	Glutamate receptor ionotropic, kainate 3	reviewed	Ion channel	GRIK3	IC50	'='	77	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	IC50	'='	77	nM
Q16099	BXGT013620	Glutamate receptor ionotropic, kainate 4	reviewed	Ion channel	GRIK4	IC50	'='	77	nM
Q16478	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	IC50	'='	77	nM
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	IC50	'='	77	nM
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	reviewed	Ion channel	GRIK1	EC50	'='	16200	nM
P42262	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	Ki	'='	12200	nM
P48058	BXGT010614	Glutamate receptor 4	reviewed	Ion channel	GRIA4	Ki	'='	1710	nM
Q16478	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	Ki	'='	80	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	IC50	'='	100000	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	IC50	'='	100000	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	IC50	'='	100000	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	IC50	'='	100000	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	EC50	'='	27000	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	730	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	4	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	4	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	4	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	4	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	4	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	Effect	'='	100	%
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	Effect	'='	100	%
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Effect	'='	100	%
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	Effect	'='	100	%
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Effect	'='	100	%
Q9R1M7	BXGT021417	Glutamate receptor ionotropic, NMDA 3A	reviewed	-	Grin3a	EC50	'='	25000	nM
Q8VHN2	BXGT018931	Glutamate receptor ionotropic, NMDA 3B	reviewed	-	Grin3b	EC50	'='	25000	nM
Q62645	BXGT016035	Glutamate receptor ionotropic, NMDA 2D	reviewed	-	Grin2d	EC50	'='	25000	nM
Q00961	BXGT012556	Glutamate receptor ionotropic, NMDA 2C	reviewed	-	Grin2c	EC50	'='	25000	nM
Q00960	BXGT012555	Glutamate receptor ionotropic, NMDA 2B	reviewed	-	Grin2b	EC50	'='	25000	nM
Q00959	BXGT012554	Glutamate receptor ionotropic, NMDA 2A	reviewed	-	Grin2a	EC50	'='	25000	nM
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	EC50	'='	25000	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Rmax	'='	100	%
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	IC50	-	-	-
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	IC50	-	-	-
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	IC50	-	-	-
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	IC50	-	-	-
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	10	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	10	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	10	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	10	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	10	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	5011	nM
P42262	BXGT010294	Glutamate receptor 2	reviewed	Ion channel	GRIA2	Ki	'='	12221	nM
O95149	BXGT005350	Snurportin-1	reviewed	-	SNUPN	Potency	-	31622	nM
Q14974	BXGT013516	Importin subunit beta-1	reviewed	Transporter	KPNB1	Potency	-	31622	nM
P0A6C1	BXGT007045	Endonuclease 4	reviewed	-	nfo	Potency	'='	15848	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	Activity	'='	15	%
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Ki	'='	3	nM
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	-5	%
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	Activity	'='	18	%
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	Activity	'='	55	%
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	EC50	'='	1800	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	Ki	'='	1980	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	Ki	'='	3690	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	Ki	'='	4	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	Ki	'='	7500	nM
P42261	BXGT010293	Glutamate receptor 1	reviewed	Ion channel	GRIA1	Ki	'='	7450	nM
P48058	BXGT010614	Glutamate receptor 4	reviewed	Ion channel	GRIA4	Ki	'='	1714	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	354	nM
P31596	BXGT009553	Excitatory amino acid transporter 2	reviewed	-	Slc1a2	Control	'='	39	%
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Ki	'='	12	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	IC50	'='	6000	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	IC50	'='	6000	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	IC50	'='	6000	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	IC50	'='	6000	nM
Q16478	BXGT013630	Glutamate receptor ionotropic, kainate 5	reviewed	Ion channel	GRIK5	Ki	'='	177	nM
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	reviewed	-	IDH1	Potency	-	29092	nM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	14125	nM
O15303	BXGT004150	Metabotropic glutamate receptor 6	reviewed	G-protein coupled receptor	GRM6	EC50	'='	299000	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	EC50	'='	12000	nM
Q13002	BXGT013303	Glutamate receptor ionotropic, kainate 2	reviewed	Ion channel	GRIK2	Ki	'='	32	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	35481	nM
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	'='	4	%
Q9R1M7	BXGT021417	Glutamate receptor ionotropic, NMDA 3A	reviewed	-	Grin3a	Activity	'='	243	%
Q8VHN2	BXGT018931	Glutamate receptor ionotropic, NMDA 3B	reviewed	-	Grin3b	Activity	'='	243	%
Q62645	BXGT016035	Glutamate receptor ionotropic, NMDA 2D	reviewed	-	Grin2d	Activity	'='	243	%
Q00961	BXGT012556	Glutamate receptor ionotropic, NMDA 2C	reviewed	-	Grin2c	Activity	'='	243	%
Q00960	BXGT012555	Glutamate receptor ionotropic, NMDA 2B	reviewed	-	Grin2b	Activity	'='	243	%
Q00959	BXGT012554	Glutamate receptor ionotropic, NMDA 2A	reviewed	-	Grin2a	Activity	'='	243	%
P35439	BXGT009831	Glutamate receptor ionotropic, NMDA 1	reviewed	-	Grin1	Activity	'='	243	%
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	EC50	'='	47000	nM
P54132	BXGT011032	Bloom syndrome protein	reviewed	-	BLM	Potency	'='	125	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Ki	'='	12	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	7499	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	106	%
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	IC50	'='	13	nM
P42264	BXGT010296	Glutamate receptor ionotropic, kainate 3	reviewed	-	Grik3	IC50	'='	13	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	IC50	'='	13	nM
Q01812	BXGT012617	Glutamate receptor ionotropic, kainate 4	reviewed	-	Grik4	IC50	'='	13	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	IC50	'='	13	nM
P42260	BXGT010292	Glutamate receptor ionotropic, kainate 2	reviewed	-	Grik2	Bmax	'='	1	pmol/mg
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	IC50	'='	2000	nM
P19493	BXGT008491	Glutamate receptor 4	reviewed	-	Gria4	IC50	'='	2000	nM
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	IC50	'='	2000	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	IC50	'='	2000	nM
Q63273	BXGT016064	Glutamate receptor ionotropic, kainate 5	reviewed	-	Grik5	Ki	'='	15	nM
P19490	BXGT008488	Glutamate receptor 1	reviewed	-	Gria1	Ki	'='	477	nM
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	17782	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	17782	nM
P19491	BXGT008489	Glutamate receptor 2	reviewed	-	Gria2	Ki	'='	6300	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	631	nM
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Activity	'='	97	%
P19492	BXGT008490	Glutamate receptor 3	reviewed	-	Gria3	Activity	'='	45	%
P22756	BXGT008804	Glutamate receptor ionotropic, kainate 1	reviewed	-	Grik1	Ki	'='	76	nM
Q9F4F7	BXGT020344	4'-phosphopantetheinyl transferase ffp	reviewed	-	ffp	Potency	'='	12589	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01333	Leontice robustum	Leontice robustum	Medicinal Plant
BXGF03359	Amomum melegueta	Amomum melegueta	Medicinal Plant
BXGF04057	Abrus pulchellus	Abrus pulchellus	Medicinal Plant
BXGF04471	Otholobium glandulosum	Otholobium glandulosum	Medicinal Plant
BXGF04483	Terminalia brachystemma	Terminalia brachystemma	Others
BXGF04494	Raoulia australis	Raoulia australis	Others
BXGF04507	Anacyclus monanthos	Anacyclus monanthos	Others
BXGF04516	Ulmus campestris	Ulmus campestris	Medicinal Plant
BXGF04554	Corydalis tashiroi	Corydalis tashiroi	Others
BXGF04562	Senecio chionophilus	Senecio chionophilus	Others
BXGF04592	Prunus speciosa	Prunus speciosa	Others
BXGF04612	Mikania cordifolia	Mikania cordifolia	Medicinal Plant
BXGF04619	Hakea trifurcata	Hakea trifurcata	Others
BXGF04624	Astragalus siculus	Astragalus siculus	Others
BXGF04652	Guizotia scabra	Guizotia scabra	Medicinal Plant
BXGF04669	Euphorbia cuneata	Euphorbia cuneata	Medicinal Plant
BXGF04672	Arum palaestinum	Arum palaestinum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}