Showing entry for Tyrosine-protein kinase Tec



                       
General Target Information
BXGT IdBXGT010329
Protein NameTyrosine-protein kinase Tec
Uniport IdP42680
GeneTEC
Gene Id7006
DomainBTK; PH; Pkinase_Tyr; SH2; SH3_1
Pfam PF00779   PF00169   PF07714   PF00017   PF00018  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
5. Organismal Systems 5.1 Immune system hsa04660 T cell receptor signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0050853 B cell receptor signaling pathway
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0038095 Fc-epsilon receptor signaling pathway
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0010543 regulation of platelet activation
Biological Process GO:0050852 T cell receptor signaling pathway
Biological Process GO:0042246 tissue regeneration
molecular function GO:0005524 ATP binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0005543 phospholipid binding
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1433557 Signaling by SCF-KIT
R-HSA-162582 Signal Transduction
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2871809 FCERI mediated Ca+2 mobilization
R-HSA-2871809 FCERI mediated Ca+2 mobilization
R-HSA-449147 Signaling by Interleukins
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein