Showing entry for Vasopressin V1b receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010596
Protein NameVasopressin V1b receptor
Uniport IdP47901
GeneAVPR1B
Gene Id553
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.3 Circulatory system hsa04270 Vascular smooth muscle contraction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007202 activation of phospholipase C activity
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0090238 positive regulation of arachidonic acid secretion
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0060732 positive regulation of inositol phosphate biosynthetic process
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0032430 positive regulation of phospholipase A2 activity
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0001992 regulation of systemic arterial blood pressure by vasopressin
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0042277 peptide binding
molecular function GO:0005080 protein kinase C binding
molecular function GO:0005000 vasopressin receptor activity
cellular component GO:0005768 endosome
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-388479 Vasopressin-like receptors
R-HSA-416476 G alpha (q) signalling events
R-HSA-500792 GPCR ligand binding
R-HSA-5619099 Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)
R-HSA-5619102 SLC transporter disorders
R-HSA-5619115 Disorders of transmembrane transporters
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001231 BXGD000034 ACTH Syndrome, Ectopic Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0025193 BXGD001831 Melancholia Mental Disorders
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0032002 BXGD002320 Pituitary Diseases Nervous System Diseases; Endocrine System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0154409 BXGD003717 Recurrent major depressive episodes Mental Disorders
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0236664 BXGD004818 Alcohol-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0236970 BXGD004843 Alcohol-Induced Disorders Chemically-Induced Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0438696 BXGD008805 Suicidal Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C2751719 BXGD017735 ALCOHOL DEPENDENCE, PROTECTION AGAINST
C3887915 BXGD019927 AERODIGESTIVE TRACT CANCER, SQUAMOUS CELL, ALCOHOL-RELATED, PROTECTION AGAINST
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000982 L-Homocysteine 135.19
BXGC0005683 Quercetin 302.24
BXGC0005874 Racemethionine 149.21
BXGC0006183 L-Cystine 240.3
BXGC0017933 Sulfuretin 270.05
BXGC0038837 Pseudohypericin 520.08
BXGC0042462 Cysteine 121.02
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein