adisease

Showing entry for Panic Disorder

General Disease Information
BXGD Id	BXGD002208
Disease Name	Panic Disorder
Disease CUI Id	C0030319
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43614	BXGT004606	Orexin receptor type 2	3062	reviewed	G-protein coupled receptor
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
P00338	BXGT005504	L-lactate dehydrogenase A chain	3939	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07195	BXGT006563	L-lactate dehydrogenase B chain	3945	reviewed	Enzyme
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07602	BXGT006646	Prosaposin	5660	reviewed
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P10909	BXGT007630	Clusterin	1191	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P12955	BXGT007865	Xaa-Pro dipeptidase	5184	reviewed	Enzyme
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P18405	BXGT008400	3-oxo-5-alpha-steroid 4-dehydrogenase 1	6715	reviewed	Enzyme
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	2562	reviewed	Ion channel
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30536	BXGT009435	Translocator protein	706	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	2558	reviewed	Ion channel
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32238	BXGT009611	Cholecystokinin receptor type A	886	reviewed	G-protein coupled receptor
P32239	BXGT009612	Gastrin/cholecystokinin type B receptor	887	reviewed	G-protein coupled receptor
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
P46663	BXGT010531	B1 bradykinin receptor	623	reviewed	G-protein coupled receptor
P47901	BXGT010596	Vasopressin V1b receptor	553	reviewed	G-protein coupled receptor
P48167	BXGT010621	Glycine receptor subunit beta	2743	reviewed	Ion channel
P49802	BXGT010746	Regulator of G-protein signaling 7	6000	reviewed
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q01118	BXGT012570	Sodium channel protein type 7 subunit alpha	6332	reviewed	Ion channel
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q04760	BXGT012782	Lactoylglutathione lyase	2739	reviewed
Q04828	BXGT012787	Aldo-keto reductase family 1 member C1	1645	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	5142	reviewed
Q07837	BXGT012943	Neutral and basic amino acid transport protein rBAT	6519	reviewed	Transporter
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q14164	BXGT013451	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	9641	reviewed	Kinase
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q15761	BXGT013596	Neuropeptide Y receptor type 5	4889	reviewed	G-protein coupled receptor
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	2559	reviewed	Ion channel
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8TET4	BXGT018823	Neutral alpha-glucosidase C	2595	reviewed	Enzyme
Q92945	BXGT019397	Far upstream element-binding protein 2	8570	reviewed	Enzyme
Q96FJ2	BXGT019659	Dynein light chain 2, cytoplasmic	140735	reviewed	Cellular structure
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q9BXD5	BXGT020166	N-acetylneuraminate lyase	80896	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9NQV5	BXGT021170	PR domain-containing protein 11	56981	reviewed
Q9UBS5	BXGT021662	Gamma-aminobutyric acid type B receptor subunit 1	2550	reviewed	G-protein coupled receptor
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
Q86XP1	BXGT022668	Diacylglycerol kinase eta	160851	reviewed	Kinase
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
O43613	BXGT025666	Orexin receptor type 1	3061	reviewed	G-protein coupled receptor
V9HWB9	BXGT026149	L-lactate dehydrogenase	3939	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}