Showing entry for Amphiphysin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010704
Protein NameAmphiphysin
Uniport IdP49418
GeneAMPH
Gene Id273
DomainBAR; SH3_9
Pfam PF03114   PF14604  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
5. Organismal Systems 5.1 Immune system hsa04666 Fc gamma R-mediated phagocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0006897 endocytosis
Biological Process GO:0061024 membrane organization
Biological Process GO:0048488 synaptic vesicle endocytosis
molecular function GO:0005543 phospholipid binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0031256 leading edge membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0030672 synaptic vesicle membrane
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0014038 BXGD000878 Encephalitis Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015464 BXGD000994 Facial Nerve Diseases Nervous System Diseases; Stomatognathic Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024301 BXGD001759 Lymphoma, Follicular Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027126 BXGD001976 Myotonic Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0037763 BXGD002699 Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085292 BXGD003153 Stiff-Person Syndrome Immune System Diseases; Nervous System Diseases
C0152025 BXGD003521 Polyneuropathy Nervous System Diseases
C0175709 BXGD004013 Centronuclear myopathy Musculoskeletal Diseases; Nervous System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0338430 BXGD007173 Limbic Encephalitis Neoplasms; Infections; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0410204 BXGD008418 Myopathy, Centronuclear, Autosomal Recessive Musculoskeletal Diseases; Nervous System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0751871 BXGD010623 Autoimmune Diseases of the Nervous System Immune System Diseases; Nervous System Diseases
C0752282 BXGD010709 Congenital Structural Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0919659 BXGD011434 Oropharyngeal candidiasis Infections
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332312 BXGD012522 Aortic Angiosarcoma
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1709353 BXGD013624 Osteofibrous Dysplasia Musculoskeletal Diseases
C3645536 BXGD019247 Autosomal Recessive Centronuclear Myopathy Musculoskeletal Diseases; Nervous System Diseases
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002591 Potassium 39.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein