adisease

Showing entry for Encephalitis

General Disease Information
BXGD Id	BXGD000878
Disease Name	Encephalitis
Disease CUI Id	C0014038
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707 HP:0002715
Human Phenotype Ontology Term	Abnormality of the nervous system; Abnormality of the immune system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00418	BXGT003918	Eukaryotic elongation factor 2 kinase	29904	reviewed	Kinase
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15553	BXGT004181	Pyrin	4210	reviewed
O43272	BXGT004580	Proline dehydrogenase 1, mitochondrial	5625	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04004	BXGT006125	Vitronectin	7448	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05090	BXGT006311	Apolipoprotein D	347	reviewed
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06734	BXGT006491	Low affinity immunoglobulin epsilon Fc receptor	2208	reviewed	Receptor
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19525	BXGT008492	Interferon-induced, double-stranded RNA-activated protein kinase	5610	reviewed	Kinase
P19652	BXGT008506	Alpha-1-acid glycoprotein 2	5005	reviewed
P20933	BXGT008618	N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	175	reviewed	Enzyme
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P22413	BXGT008764	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	5167	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23786	BXGT008906	Carnitine O-palmitoyltransferase 2, mitochondrial	1376	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30536	BXGT009435	Translocator protein	706	reviewed
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35613	BXGT009856	Basigin	682	reviewed
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43354	BXGT010381	Nuclear receptor subfamily 4 group A member 2	4929	reviewed	Nuclear receptor
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P49418	BXGT010704	Amphiphysin	273	reviewed
P49591	BXGT010715	Serine--tRNA ligase, cytoplasmic	6301	reviewed	Enzyme
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P51572	BXGT010859	B-cell receptor-associated protein 31	10134	reviewed	Transporter
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P80075	BXGT011876	C-C motif chemokine 8	6355	reviewed	Signaling
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
P81172	BXGT011935	Hepcidin	57817	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q06418	BXGT012875	Tyrosine-protein kinase receptor TYRO3	7301	reviewed	Kinase
Q07157	BXGT012920	Tight junction protein ZO-1	7082	reviewed	Cell-cell junction
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13637	BXGT013388	Ras-related protein Rab-32	10981	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14624	BXGT013491	Inter-alpha-trypsin inhibitor heavy chain H4	3700	reviewed	Enzyme modulator
Q14653	BXGT013494	Interferon regulatory factor 3	3661	reviewed	Transcription factor
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15835	BXGT013606	Rhodopsin kinase	6011	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q6QHF9	BXGT016497	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	196743	reviewed
Q86UE8	BXGT017612	Serine/threonine-protein kinase tousled-like 2	11011	reviewed	Kinase
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q96Q83	BXGT019715	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	221120	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9NPG2	BXGT021155	Neuroglobin	58157	reviewed	Transporter
Q9NPH2	BXGT021158	Inositol-3-phosphate synthase 1	51477	reviewed
Q9NWM0	BXGT021232	Spermine oxidase	54498	reviewed
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9UBN7	BXGT021658	Histone deacetylase 6	10013	reviewed	Epigenetic regulator
Q9UBS5	BXGT021662	Gamma-aminobutyric acid type B receptor subunit 1	2550	reviewed	G-protein coupled receptor
Q9UDY8	BXGT021670	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	10892	reviewed	Enzyme
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
Q99748	BXGT023217	Neurturin	4902	reviewed	Signaling
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
A6NGN9	BXGT023893	IgLON family member 5	402665	reviewed
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q695T7	BXGT024794	Sodium-dependent neutral amino acid transporter B(0)AT1	340024	reviewed
Q68DU8	BXGT024810	BTB/POZ domain-containing protein KCTD16	57528	reviewed	Enzyme modulator
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}