adisease

Showing entry for Polyneuropathy

General Disease Information
BXGD Id	BXGD003521
Disease Name	Polyneuropathy
Disease CUI Id	C0152025
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00764	BXGT003948	Pyridoxal kinase	8566	reviewed	Kinase
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O43323	BXGT004587	Desert hedgehog protein	50846	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O75112	BXGT005099	LIM domain-binding protein 3	11155	reviewed	Cellular structure
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P00156	BXGT005469	Cytochrome b	4519	reviewed
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03891	BXGT006110	NADH-ubiquinone oxidoreductase chain 2	4536	reviewed
P03901	BXGT006112	NADH-ubiquinone oxidoreductase chain 4L	4539	reviewed	Enzyme
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05543	BXGT006366	Thyroxine-binding globulin	6906	reviewed	Enzyme modulator
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07602	BXGT006646	Prosaposin	5660	reviewed
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P29401	BXGT009344	Transketolase	7086	reviewed	Enzyme
P48506	BXGT010635	Glutamate--cysteine ligase catalytic subunit	2729	reviewed	Enzyme
P49418	BXGT010704	Amphiphysin	273	reviewed
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q12923	BXGT013281	Tyrosine-protein phosphatase non-receptor type 13	5783	reviewed
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15120	BXGT013542	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	5165	reviewed	Kinase
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6PI48	BXGT016471	Aspartate--tRNA ligase, mitochondrial	55157	reviewed	Enzyme
Q8N159	BXGT018496	N-acetylglutamate synthase, mitochondrial	162417	reviewed
Q92859	BXGT019386	Neogenin	4756	reviewed
Q96CW9	BXGT019634	Netrin-G2	84628	reviewed	Enzyme modulator
Q96IV0	BXGT019677	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	55768	reviewed	Enzyme
Q96SW2	BXGT019743	Protein cereblon	51185	reviewed	Enzyme
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9H816	BXGT020494	5' exonuclease Apollo	64858	reviewed
Q9HCG8	BXGT020534	Pre-mRNA-splicing factor CWC22 homolog	57703	reviewed	Enzyme
Q9NZJ4	BXGT021274	Sacsin	26278	reviewed
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9UHD8	BXGT021698	Septin-9	10801	reviewed	Enzyme modulator
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P35240	BXGT022927	Merlin	4771	reviewed
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}