Showing entry for Serine/threonine-protein kinase Nek4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010910
Protein NameSerine/threonine-protein kinase Nek4
Uniport IdP51957
GeneNEK4
Gene Id6787
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0051301 cell division
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0000278 mitotic cell cycle
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:2000772 regulation of cellular senescence
Biological Process GO:1900062 regulation of replicative cell aging
Biological Process GO:2001020 regulation of response to DNA damage stimulus
molecular function GO:0005524 ATP binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0036064 ciliary basal body
cellular component GO:0097014 ciliary plasm
cellular component GO:0035253 ciliary rootlet
cellular component GO:0035869 ciliary transition zone
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038002 BXGD002723 Splenomegaly Pathological Conditions, Signs and Symptoms
C0206161 BXGD004167 Reticulocyte count (procedure)
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1305855 BXGD012348 Body mass index
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1319315 BXGD012415 Adenocarcinoma of large intestine Digestive System Diseases; Neoplasms
C1865190 BXGD016297 Mild splenomegaly
C2985280 BXGD018223 Blood Protein Measurement
C4277690 BXGD022377 Ciliopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0044857 Sp-600125 220.06
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein