Showing entry for Amyloid-beta A4 precursor protein-binding family A member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012652
Protein NameAmyloid-beta A4 precursor protein-binding family A member 1
Uniport IdQ02410
GeneAPBA1
Gene Id320
DomainPDZ; PID
Pfam PF00595   PF00640  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008088 axo-dendritic transport
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0014051 gamma-aminobutyric acid secretion
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0007399 nervous system development
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
molecular function GO:0001540 amyloid-beta binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005634 nucleus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0098685 Schaffer collateral - CA1 synapse
cellular component GO:0045202 synapse
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
R-HSA-112310 Neurotransmitter release cycle
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
R-HSA-212676 Dopamine Neurotransmitter Release Cycle
R-HSA-442755 Activation of NMDA receptors and postsynaptic events
R-HSA-6794361 Neurexins and neuroligins
R-HSA-6794362 Protein-protein interactions at synapses
R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0007097 BXGD000424 Carcinoma Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0333983 BXGD006975 Hyperplastic Polyp Pathological Conditions, Signs and Symptoms
C0410702 BXGD008447 Adolescent idiopathic scoliosis Musculoskeletal Diseases
C0596887 BXGD009648 mathematical ability
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C1333990 BXGD012670 Hereditary Nonpolyposis Colorectal Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1837461 BXGD014234 SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
C3887551 BXGD019898 Memory dysfunction Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001965 Hesperidin 610.56
BXGC0018467 (6R,7R)-7-(4-Carboxybutanoylamino)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid 328.07
BXGC0024988 Nifedipine 346.12
BXGC0042397 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-Methyl-2,3-Dihydrochromen-4-One 286.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein