Showing entry for Voltage-dependent L-type calcium channel subunit alpha-1S


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012654
Protein NameVoltage-dependent L-type calcium channel subunit alpha-1S
Uniport IdQ02485
GeneCacna1s
Gene Id682930
DomainCa_chan_IQ; GPHH; Ion_trans
Pfam PF08763   PF16905   PF00520  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070509 calcium ion import
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0071313 cellular response to caffeine
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0002074 extraocular skeletal muscle development
Biological Process GO:0055001 muscle cell development
Biological Process GO:0006936 muscle contraction
Biological Process GO:0007520 myoblast fusion
Biological Process GO:0007528 neuromuscular junction development
Biological Process GO:0001503 ossification
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0043501 skeletal muscle adaptation
Biological Process GO:0048741 skeletal muscle fiber development
Biological Process GO:0007519 skeletal muscle tissue development
Biological Process GO:0001501 skeletal system development
Biological Process GO:0006941 striated muscle contraction
molecular function GO:0005516 calmodulin binding
molecular function GO:0008331 high voltage-gated calcium channel activity
molecular function GO:0046872 metal ion binding
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0005737 cytoplasm
cellular component GO:0044327 dendritic spine head
cellular component GO:0031674 I band
cellular component GO:1990454 L-type voltage-gated calcium channel complex
cellular component GO:0005886 plasma membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0030315 T-tubule
cellular component GO:0005891 voltage-gated calcium channel complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001591 (+)-O-Methylarmepavine 327.42
BXGC0003464 Satiomem 290.79
BXGC0005139 Cyclocurcumin 368.38
BXGC0005611 Coclaurine 285.34
BXGC0005724 Demethoxycurcumin 338.35
BXGC0005982 Curcumin 368.38
BXGC0014455 Fanchinin 622.3
BXGC0024245 4-[(6,7-Dimethoxy-2-Methyl-3,4-Dihydro-1H-Isoquinolin-1-Yl)Methyl]Phenol 313.17
BXGC0024988 Nifedipine 346.12
BXGC0027118 Tamsulosin 408.17
BXGC0043126 Nicardipine 479.21
BXGC0044017 Verapamil 454.28
BXGC0048241 4-[(6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenol 299.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein