Showing entry for Non-receptor tyrosine-protein kinase TNK1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013359
Protein NameNon-receptor tyrosine-protein kinase TNK1
Uniport IdQ13470
GeneTNK1
Gene Id8711
DomainPkinase_Tyr
Pfam PF07714  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030154 cell differentiation
Biological Process GO:0045087 innate immune response
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0046580 negative regulation of Ras protein signal transduction
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C1332977 BXGD012569 Childhood Leukemia Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein