Showing entry for Prostaglandin reductase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013513
Protein NameProstaglandin reductase 1
Uniport IdQ14914
GenePTGR1
Gene Id22949
DomainADH_N_2; ADH_zinc_N
Pfam PF16884   PF00107  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006691 leukotriene metabolic process
Biological Process GO:0006693 prostaglandin metabolic process
Biological Process GO:0097327 response to antineoplastic agent
molecular function GO:0036132 13-prostaglandin reductase activity
molecular function GO:0047522 15-oxoprostaglandin 13-oxidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0070062 extracellular exosome
molecular function GO:0032440 2-alkenal reductase NAD(P)+ activity
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-HSA-2142700 Synthesis of Lipoxins (LX)
R-HSA-2142753 Arachidonic acid metabolism
R-HSA-556833 Metabolism of lipids
R-HSA-8978868 Fatty acid metabolism
R-HSA-9018678 Biosynthesis of specialized proresolving mediators (SPMs)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005890 BXGD000345 Body Height
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0023904 BXGD001721 Liver Neoplasms, Experimental Digestive System Diseases; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0200637 BXGD004042 Monocyte count procedure
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0750880 BXGD010239 Monocyte count result
C1290886 BXGD012200 Chronic inflammatory disorder Pathological Conditions, Signs and Symptoms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1629609 BXGD013479 Age at menopause
C1654637 BXGD013484 androgen independent prostate cancer
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3887506 BXGD019886 Hyperkinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001889 p-Coumaric acid 164.16
BXGC0003705 Chloride 35.45
BXGC0019164 Raloxifene 473.17
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein