Showing entry for Ribosomal oxygenase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018334
Protein NameRibosomal oxygenase 2
Uniport IdQ8IUF8
GeneRIOX2
Gene Id84864
DomainCupin_4
Pfam PF08007  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042254 ribosome biogenesis
molecular function GO:0051864 histone demethylase activity (H3-K36 specific)
molecular function GO:0032453 histone demethylase activity (H3-K4 specific)
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0003714 transcription corepressor activity
cellular component GO:0005829 cytosol
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005667 transcription regulator complex
Reactome
Pathway Id Pathway Name
R-HSA-3214842 HDMs demethylate histones
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0003855 BXGD000227 Arteriovenous fistula Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0008533 BXGD000556 Hemophilia B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0017154 BXGD001097 Gastritis, Atrophic Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027583 BXGD002001 Nematode infections Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0265110 BXGD005455 Cerebral Vasospasm Nervous System Diseases; Cardiovascular Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280255 BXGD006729 stage, endometrial carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0332853 BXGD006901 Anastomosis
C0334037 BXGD006980 Intestinal metaplasia
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0521158 BXGD009130 Recurrent tumor
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0949541 BXGD011578 Hurthle Cell Tumor Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1306837 BXGD012377 Papillary Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4727069 BXGD023850 Advanced Renal Cell Carcinoma
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002485 2-Oxopentanedioic acid 146.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein