Showing entry for 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018816
Protein Name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
Uniport IdQ8TDX5
GeneACMSD
Gene Id130013
DomainAmidohydro_2
Pfam PF04909  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1904985 negative regulation of quinolinate biosynthetic process
Biological Process GO:1905004 picolinic acid biosynthetic process
Biological Process GO:1905012 regulation of 'de novo' NAD biosynthetic process from tryptophan
Biological Process GO:0019748 secondary metabolic process
Biological Process GO:0006569 tryptophan catabolic process
molecular function GO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity
molecular function GO:0016831 carboxy-lyase activity
molecular function GO:0016787 hydrolase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71240 Tryptophan catabolism
R-HSA-71291 Metabolism of amino acids and derivatives
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0018935 BXGD001252 Hematocrit procedure
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0162701 BXGD003978 Polysomnography
C0201899 BXGD004056 Aspartate aminotransferase measurement
C0202231 BXGD004085 Thyroxine measurement
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0428883 BXGD008639 Diastolic blood pressure
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3698239 BXGD019368 Cerebral cortex myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4317109 BXGD022725 Epileptic Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0001096 Dihydroxyacetone phosphate 170.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein