Showing entry for Epileptic Seizures


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD022725
Disease NameEpileptic Seizures
Disease CUI IdC4317109
MeSH Codes C23   C10  
Disease Class NamePathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00305 BXGT003907 Voltage-dependent L-type calcium channel subunit beta-4 785 reviewed Ion channel
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase 29904 reviewed Kinase
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14558 BXGT004070 Heat shock protein beta-6 126393 reviewed
O14842 BXGT004106 Free fatty acid receptor 1 2864 reviewed G-protein coupled receptor
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O76039 BXGT005171 Cyclin-dependent kinase-like 5 6792 reviewed Kinase
O95278 BXGT005370 Laforin 7957 reviewed
O95970 BXGT005409 Leucine-rich glioma-inactivated protein 1 9211 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01308 BXGT005749 Insulin 3630 reviewed
P01574 BXGT005768 Interferon beta 3456 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05186 BXGT006338 Alkaline phosphatase, tissue-nonspecific isozyme 249 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06276 BXGT006430 Cholinesterase 590 reviewed
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P0CG48 BXGT007468 Polyubiquitin-C 7316 reviewed Nucleic acid binding
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 1128 reviewed G-protein coupled receptor
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P13639 BXGT007934 Elongation factor 2 1938 reviewed Enzyme
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15085 BXGT008077 Carboxypeptidase A1 1357 reviewed Enzyme
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16389 BXGT008221 Potassium voltage-gated channel subfamily A member 2 3737 reviewed Ion channel
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19021 BXGT008449 Peptidyl-glycine alpha-amidating monooxygenase 5066 reviewed Enzyme
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P24752 BXGT008993 Acetyl-CoA acetyltransferase, mitochondrial 38 reviewed Enzyme
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25713 BXGT009062 Metallothionein-3 4504 reviewed
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P29218 BXGT009322 Inositol monophosphatase 1 3612 reviewed Enzyme
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30531 BXGT009432 Sodium- and chloride-dependent GABA transporter 1 6529 reviewed Transporter
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 1143 reviewed Ion channel
P31644 BXGT009557 Gamma-aminobutyric acid receptor subunit alpha-5 2558 reviewed Ion channel
P32297 BXGT009616 Neuronal acetylcholine receptor subunit alpha-3 1136 reviewed Ion channel
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P34903 BXGT009769 Gamma-aminobutyric acid receptor subunit alpha-3 2556 reviewed Ion channel
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35368 BXGT009822 Alpha-1B adrenergic receptor 147 reviewed G-protein coupled receptor
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P39086 BXGT010093 Glutamate receptor ionotropic, kainate 1 2897 reviewed Ion channel
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P42261 BXGT010293 Glutamate receptor 1 2890 reviewed Ion channel
P42262 BXGT010294 Glutamate receptor 2 2891 reviewed Ion channel
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49448 BXGT010709 Glutamate dehydrogenase 2, mitochondrial 2747 reviewed Enzyme
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P50993 BXGT010826 Sodium/potassium-transporting ATPase subunit alpha-2 477 reviewed Transporter
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P60903 BXGT011339 Protein S100-A10 6281 reviewed Calcium-binding protein
P62979 BXGT011476 Ubiquitin-40S ribosomal protein S27a 6233 reviewed Nucleic acid binding
P68363 BXGT011594 Tubulin alpha-1B chain 10376 reviewed Cellular structure
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
P80404 BXGT011907 4-aminobutyrate aminotransferase, mitochondrial 18 reviewed Enzyme
P98177 BXGT012232 Forkhead box protein O4 4303 reviewed
Q05193 BXGT012810 Dynamin-1 1759 reviewed Enzyme modulator
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13237 BXGT013331 cGMP-dependent protein kinase 2 5593 reviewed Kinase
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q13621 BXGT013383 Solute carrier family 12 member 1 6557 reviewed Transporter
Q14353 BXGT013463 Guanidinoacetate N-methyltransferase 2593 reviewed
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q14832 BXGT013507 Metabotropic glutamate receptor 3 2913 reviewed G-protein coupled receptor
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15599 BXGT013583 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 9351 reviewed
Q16099 BXGT013620 Glutamate receptor ionotropic, kainate 4 2900 reviewed Ion channel
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q71U36 BXGT016705 Tubulin alpha-1A chain 7846 reviewed Cellular structure
Q8IVA8 BXGT018342 Glutamate decarboxylase 1 (Brain, 67kDa) 2571 unreviewed
Q8IXI2 BXGT018361 Mitochondrial Rho GTPase 1 55288 reviewed Enzyme modulator
Q8TDX5 BXGT018816 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 130013 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99259 BXGT019915 Glutamate decarboxylase 1 2571 reviewed Enzyme
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9H2X9 BXGT020459 Solute carrier family 12 member 5 57468 reviewed Transporter
Q9H8M5 BXGT020496 Metal transporter CNNM2 54805 reviewed
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NQX3 BXGT021172 Gephyrin 10243 reviewed
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9NWM0 BXGT021232 Spermine oxidase 54498 reviewed
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha 6328 reviewed Ion channel
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9UPT6 BXGT021801 C-Jun-amino-terminal kinase-interacting protein 3 23162 reviewed Enzyme modulator
Q9UPY5 BXGT021803 Cystine/glutamate transporter 23657 reviewed Transporter
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
Q86US8 BXGT022850 Telomerase-binding protein EST1A 23293 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
O14649 BXGT025486 Potassium channel subfamily K member 3 3777 reviewed Ion channel
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease