Showing entry for Diabetes Mellitus, Experimental


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000752
Disease NameDiabetes Mellitus, Experimental
Disease CUI IdC0011853
MeSH Codes C18   C19  
Disease Class NameNutritional and Metabolic Diseases; Endocrine System Diseases
Semantic TypeExperimental Model of Disease
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O15067 BXGT004123 Phosphoribosylformylglycinamidine synthase 5198 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15217 BXGT004137 Glutathione S-transferase A4 2941 reviewed
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15294 BXGT004147 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 8473 reviewed
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O15554 BXGT004182 Intermediate conductance calcium-activated potassium channel protein 4 3783 reviewed Ion channel
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43826 BXGT004629 Glucose-6-phosphate exchanger SLC37A4 2542 reviewed Transporter
O43868 BXGT004631 Sodium/nucleoside cotransporter 2 9153 reviewed Transporter
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60563 BXGT004883 Cyclin-T1 904 reviewed Enzyme modulator
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60706 BXGT004896 ATP-binding cassette sub-family C member 9 10060 reviewed Transporter
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O60895 BXGT004907 Receptor activity-modifying protein 2 10266 reviewed Receptor
O75306 BXGT005108 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial 4720 reviewed Enzyme
O75489 BXGT005131 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial 4722 reviewed
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 7367 reviewed
O75908 BXGT005162 Sterol O-acyltransferase 2 8435 reviewed Enzyme
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00156 BXGT005469 Cytochrome b 4519 reviewed
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00480 BXGT005551 Ornithine carbamoyltransferase, mitochondrial 5009 reviewed
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P00966 BXGT005707 Argininosuccinate synthase 445 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02671 BXGT005914 Fibrinogen alpha chain 2243 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05062 BXGT006305 Fructose-bisphosphate aldolase B 229 reviewed
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05161 BXGT006331 Ubiquitin-like protein ISG15 9636 reviewed Nucleic acid binding
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06276 BXGT006430 Cholinesterase 590 reviewed
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial 506 reviewed Transporter
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P08709 BXGT006818 Coagulation factor VII 2155 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P09417 BXGT006888 Dihydropteridine reductase 5860 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P09958 BXGT006950 Furin 5045 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11086 BXGT007652 Phenylethanolamine N-methyltransferase 5409 reviewed Enzyme
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11168 BXGT007663 Solute carrier family 2, facilitated glucose transporter member 2 6514 reviewed Transporter
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11172 BXGT007665 Uridine 5'-monophosphate synthase 7372 reviewed
P11217 BXGT007674 Glycogen phosphorylase, muscle form 5837 reviewed Enzyme
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P11488 BXGT007713 Guanine nucleotide-binding protein G(t) subunit alpha-1 2779 reviewed Enzyme modulator
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12694 BXGT007835 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 593 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13196 BXGT007886 5-aminolevulinate synthase, nonspecific, mitochondrial 211 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13639 BXGT007934 Elongation factor 2 1938 reviewed Enzyme
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16152 BXGT008201 Carbonyl reductase [NADPH] 1 873 reviewed
P16389 BXGT008221 Potassium voltage-gated channel subfamily A member 2 3737 reviewed Ion channel
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19174 BXGT008467 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 5335 reviewed Enzyme
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19367 BXGT008476 Hexokinase-1 3098 reviewed Kinase
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P19801 BXGT008516 Amiloride-sensitive amine oxidase [copper-containing] 26 reviewed
P20248 BXGT008554 Cyclin-A2 890 reviewed Enzyme modulator
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21953 BXGT008711 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 594 reviewed Enzyme
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22352 BXGT008758 Glutathione peroxidase 3 2878 reviewed Enzyme
P22460 BXGT008774 Potassium voltage-gated channel subfamily A member 5 3741 reviewed Ion channel
P22626 BXGT008787 Heterogeneous nuclear ribonucleoproteins A2/B1 3181 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23946 BXGT008932 Chymase 1215 reviewed Enzyme
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25705 BXGT009060 ATP synthase subunit alpha, mitochondrial 498 reviewed Transporter
P25929 BXGT009078 Neuropeptide Y receptor type 1 4886 reviewed G-protein coupled receptor
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha 5295 reviewed Kinase
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30281 BXGT009416 G1/S-specific cyclin-D3 896 reviewed Enzyme modulator
P30411 BXGT009424 B2 bradykinin receptor 624 reviewed G-protein coupled receptor
P30542 BXGT009436 Adenosine receptor A1 134 reviewed G-protein coupled receptor
P30566 BXGT009446 Adenylosuccinate lyase 158 reviewed Enzyme
P30613 BXGT009447 Pyruvate kinase PKLR 5313 reviewed Kinase
P30872 BXGT009474 Somatostatin receptor type 1 6751 reviewed G-protein coupled receptor
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31327 BXGT009523 Carbamoyl-phosphate synthase [ammonia], mitochondrial 1373 reviewed Enzyme
P31415 BXGT009537 Calsequestrin-1 844 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32239 BXGT009612 Gastrin/cholecystokinin type B receptor 887 reviewed G-protein coupled receptor
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P32745 BXGT009663 Somatostatin receptor type 3 6753 reviewed G-protein coupled receptor
P33121 BXGT009692 Long-chain-fatty-acid--CoA ligase 1 2180 reviewed Enzyme
P33176 BXGT009699 Kinesin-1 heavy chain 3799 reviewed Cellular structure
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35346 BXGT009813 Somatostatin receptor type 5 6755 reviewed G-protein coupled receptor
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35558 BXGT009847 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] 5105 reviewed Kinase
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P35914 BXGT009880 Hydroxymethylglutaryl-CoA lyase, mitochondrial 3155 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P41743 BXGT010270 Protein kinase C iota type 5584 reviewed Kinase
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P46020 BXGT010499 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform 5255 reviewed Kinase
P46663 BXGT010531 B1 bradykinin receptor 623 reviewed G-protein coupled receptor
P46734 BXGT010537 Dual specificity mitogen-activated protein kinase kinase 3 5606 reviewed Kinase
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48546 BXGT010642 Gastric inhibitory polypeptide receptor 2696 reviewed G-protein coupled receptor
P49146 BXGT010681 Neuropeptide Y receptor type 2 4887 reviewed G-protein coupled receptor
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49840 BXGT010749 Glycogen synthase kinase-3 alpha 2931 reviewed Kinase
P49915 BXGT010763 GMP synthase [glutamine-hydrolyzing] 8833 reviewed Enzyme
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50053 BXGT010769 Ketohexokinase 3795 reviewed Kinase
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 5608 reviewed Kinase
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54868 BXGT011090 Hydroxymethylglutaryl-CoA synthase, mitochondrial 3158 reviewed
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55212 BXGT011112 Caspase-6 839 reviewed Enzyme
P55263 BXGT011115 Adenosine kinase 132 reviewed Kinase
P55318 BXGT011119 Hepatocyte nuclear factor 3-gamma 3171 reviewed Transcription factor
P55809 BXGT011127 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial 5019 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60880 BXGT011335 Synaptosomal-associated protein 25 6616 reviewed Transporter
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P61978 BXGT011399 Heterogeneous nuclear ribonucleoprotein K 3190 reviewed Enzyme
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80404 BXGT011907 4-aminobutyrate aminotransferase, mitochondrial 18 reviewed Enzyme
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit 4791 reviewed Transcription factor
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01581 BXGT012599 Hydroxymethylglutaryl-CoA synthase, cytoplasmic 3157 reviewed
Q01970 BXGT012627 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 5331 reviewed Enzyme
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial 1723 reviewed Enzyme
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q02643 BXGT012660 Growth hormone-releasing hormone receptor 2692 reviewed G-protein coupled receptor
Q02928 BXGT012680 Cytochrome P450 4A11 1579 reviewed Enzyme
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04917 BXGT012791 14-3-3 protein eta 7533 reviewed Chaperone
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q06203 BXGT012862 Amidophosphoribosyltransferase 5471 reviewed Enzyme
Q06210 BXGT012864 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 2673 reviewed Enzyme
Q07157 BXGT012920 Tight junction protein ZO-1 7082 reviewed Cell-cell junction
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14432 BXGT013469 cGMP-inhibited 3',5'-cyclic phosphodiesterase A 5139 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14654 BXGT013495 ATP-sensitive inward rectifier potassium channel 11 3767 reviewed Ion channel
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15067 BXGT013532 Peroxisomal acyl-coenzyme A oxidase 1 51 reviewed Enzyme
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15493 BXGT013575 Regucalcin 9104 reviewed Enzyme
Q15835 BXGT013606 Rhodopsin kinase 6011 reviewed Kinase
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16654 BXGT013650 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 5166 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16774 BXGT013668 Guanylate kinase 2987 reviewed Kinase
Q16836 BXGT013679 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 3033 reviewed
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q5JAM2 BXGT015430 5-aminolevulinate synthase 211 unreviewed
Q5T6L4 BXGT015848 Argininosuccinate synthase 1 isoform 1 445 unreviewed
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q8N142 BXGT018495 Adenylosuccinate synthetase isozyme 1 122622 reviewed Enzyme
Q8TDX5 BXGT018816 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 130013 reviewed
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99757 BXGT019959 Thioredoxin, mitochondrial 25828 reviewed Enzyme
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZX2 BXGT020204 Uridine-cytidine kinase 2 7371 reviewed Kinase
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9HAS3 BXGT020507 Solute carrier family 28 member 3 64078 reviewed Transporter
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9UHC9 BXGT021696 NPC1-like intracellular cholesterol transporter 1 29881 reviewed Transporter
Q9UL51 BXGT021754 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 610 reviewed Ion channel
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y5K5 BXGT022295 Ubiquitin carboxyl-terminal hydrolase isozyme L5 51377 reviewed Enzyme
Q96QD8 BXGT022647 Sodium-coupled neutral amino acid transporter 2 54407 reviewed Transporter
Q9UBN1 BXGT022653 Voltage-dependent calcium channel gamma-4 subunit 27092 reviewed Ion channel
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
F1T0I5 BXGT022675 Arylalkylamine N-acetyltransferase (Serotonin N-acetyltransferase) 15 unreviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P16615 BXGT023653 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 488 reviewed Transporter
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
Q92729 BXGT025605 Receptor-type tyrosine-protein phosphatase U 10076 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease