Showing entry for Programmed cell death 6-interacting protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018994
Protein NameProgrammed cell death 6-interacting protein
Uniport IdQ8WUM4
GenePDCD6IP
Gene Id10015
DomainALIX_LYPXL_bnd; BRO1
Pfam PF13949   PF03097  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000915 actomyosin contractile ring assembly
Biological Process GO:0006915 apoptotic process
Biological Process GO:0070830 bicellular tight junction assembly
Biological Process GO:0045199 maintenance of epithelial cell apical/basal polarity
Biological Process GO:0061952 midbody abscission
Biological Process GO:0000281 mitotic cytokinesis
Biological Process GO:0036258 multivesicular body assembly
Biological Process GO:1903543 positive regulation of exosomal secretion
Biological Process GO:1903553 positive regulation of extracellular exosome assembly
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0015031 protein transport
Biological Process GO:0010824 regulation of centrosome duplication
Biological Process GO:1903551 regulation of extracellular exosome assembly
Biological Process GO:0090559 regulation of membrane permeability
Biological Process GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
Biological Process GO:0046755 viral budding
Biological Process GO:0039702 viral budding via host ESCRT complex
Biological Process GO:0019058 viral life cycle
molecular function GO:0048306 calcium-dependent protein binding
molecular function GO:0031871 proteinase activated receptor binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0042641 actomyosin
cellular component GO:0005923 bicellular tight junction
cellular component GO:0005829 cytosol
cellular component GO:0070971 endoplasmic reticulum exit site
cellular component GO:0070062 extracellular exosome
cellular component GO:1903561 extracellular vesicle
cellular component GO:0090543 Flemming body
cellular component GO:0005925 focal adhesion
cellular component GO:0001772 immunological synapse
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0042470 melanosome
cellular component GO:0016020 membrane
cellular component GO:0005815 microtubule organizing center
Reactome
Pathway Id Pathway Name
R-HSA-162587 HIV Life Cycle
R-HSA-162588 Budding and maturation of HIV virion
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-1643685 Disease
R-HSA-5210891 Uptake and function of anthrax toxins
R-HSA-5213460 RIPK1-mediated regulated necrosis
R-HSA-5218859 Regulated Necrosis
R-HSA-5339562 Uptake and actions of bacterial toxins
R-HSA-5357801 Programmed Cell Death
R-HSA-5663205 Infectious disease
R-HSA-5675482 Regulation of necroptotic cell death
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010709 BXGD000689 Cyst Pathological Conditions, Signs and Symptoms; Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0037769 BXGD002701 West Syndrome Nervous System Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0086743 BXGD003308 Osteoarthrosis Deformans Musculoskeletal Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205682 BXGD004105 Waist-Hip Ratio
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0232197 BXGD004536 Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0343641 BXGD007636 Human papilloma virus infection Infections
C0558356 BXGD009453 Malignant melanoma of eye Neoplasms; Eye Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1707444 BXGD013586 Columnar Cell Change of the Breast
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3642347 BXGD019246 Basal-Like Breast Carcinoma
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4048329 BXGD021904 Immunosuppression
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein