Showing entry for Cholangiocarcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004248
Disease NameCholangiocarcinoma
Disease CUI IdC0206698
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0025031   HP:0002664  
Human Phenotype Ontology TermAbnormality of the digestive system; Neoplasm
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O00512 BXGT003933 B-cell CLL/lymphoma 9 protein 607 reviewed
O00748 BXGT003942 Cocaine esterase 8824 reviewed Enzyme
O14684 BXGT004082 Prostaglandin E synthase 9536 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 9201 reviewed Kinase
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15264 BXGT004144 Mitogen-activated protein kinase 13 5603 reviewed Kinase
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 57016 reviewed Enzyme
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60285 BXGT004867 NUAK family SNF1-like kinase 1 9891 reviewed Kinase
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75223 BXGT005106 Gamma-glutamylcyclotransferase 79017 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
O95405 BXGT005379 Zinc finger FYVE domain-containing protein 9 9372 reviewed
O95407 BXGT005380 Tumor necrosis factor receptor superfamily member 6B 8771 reviewed
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00966 BXGT005707 Argininosuccinate synthase 445 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02730 BXGT005935 Band 3 anion transport protein 6521 reviewed Transporter
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02750 BXGT005942 Leucine-rich alpha-2-glycoprotein 116844 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04075 BXGT006145 Fructose-bisphosphate aldolase A 226 reviewed
P04083 BXGT006147 Annexin A1 301 reviewed
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05543 BXGT006366 Thyroxine-binding globulin 6906 reviewed Enzyme modulator
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06239 BXGT006427 Tyrosine-protein kinase Lck 3932 reviewed Kinase
P06493 BXGT006445 Cyclin-dependent kinase 1 983 reviewed Kinase
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07478 BXGT006630 Trypsin-2 5645 reviewed Enzyme
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08134 BXGT006728 Rho-related GTP-binding protein RhoC 389 reviewed Enzyme modulator
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08195 BXGT006745 4F2 cell-surface antigen heavy chain 6520 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08559 BXGT006788 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 5160 reviewed
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08637 BXGT006802 Low affinity immunoglobulin gamma Fc region receptor III-A 2214 reviewed Cell adhesion
P08670 BXGT006810 Vimentin 7431 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09467 BXGT006893 Fructose-1,6-bisphosphatase 1 2203 reviewed Enzyme
P09493 BXGT006900 Tropomyosin alpha-1 chain 7168 reviewed Cellular structure
P09525 BXGT006901 Annexin A4 307 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11172 BXGT007665 Uridine 5'-monophosphate synthase 7372 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13631 BXGT007929 Retinoic acid receptor gamma 5916 reviewed Nuclear receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14625 BXGT008029 Endoplasmin 7184 reviewed Chaperone
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 891 reviewed Enzyme modulator
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P15941 BXGT008176 Mucin-1 4582 reviewed
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16070 BXGT008186 CD44 antigen 960 reviewed
P16152 BXGT008201 Carbonyl reductase [NADPH] 1 873 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha 5566 reviewed Kinase
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18440 BXGT008404 Arylamine N-acetyltransferase 1 9 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19652 BXGT008506 Alpha-1-acid glycoprotein 2 5005 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21439 BXGT008649 Phosphatidylcholine translocator ABCB4 5244 reviewed Transporter
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22392 BXGT008762 Nucleoside diphosphate kinase B 654364 reviewed Kinase
P22455 BXGT008772 Fibroblast growth factor receptor 4 2264 reviewed Kinase
P22694 BXGT008797 cAMP-dependent protein kinase catalytic subunit beta 5567 reviewed Kinase
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P24864 BXGT009000 G1/S-specific cyclin-E1 898 reviewed Enzyme modulator
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25788 BXGT009070 Proteasome subunit alpha type-3 5684 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29034 BXGT009309 Protein S100-A2 6273 reviewed Calcium-binding protein
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30041 BXGT009393 Peroxiredoxin-6 9588 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31947 BXGT009589 14-3-3 protein sigma 2810 reviewed Chaperone
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P32320 BXGT009622 Cytidine deaminase 978 reviewed Enzyme
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P34059 BXGT009749 N-acetylgalactosamine-6-sulfatase 2588 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35052 BXGT009788 Glypican-1 2817 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35414 BXGT009829 Apelin receptor 187 reviewed G-protein coupled receptor
P35613 BXGT009856 Basigin 682 reviewed
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 5605 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40199 BXGT010166 Carcinoembryonic antigen-related cell adhesion molecule 6 4680 reviewed
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P41743 BXGT010270 Protein kinase C iota type 5584 reviewed Kinase
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P45973 BXGT010492 Chromobox protein homolog 5 23468 reviewed Epigenetic regulator
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P47895 BXGT010593 Aldehyde dehydrogenase family 1 member A3 220 reviewed Enzyme
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49792 BXGT010743 E3 SUMO-protein ligase RanBP2 5903 reviewed Enzyme modulator
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50225 BXGT010781 Sulfotransferase 1A1 6817 reviewed
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50613 BXGT010815 Cyclin-dependent kinase 7 1022 reviewed Kinase
P51149 BXGT010835 Ras-related protein Rab-7a 7879 reviewed
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 4751 reviewed Kinase
P52292 BXGT010925 Importin subunit alpha-1 3838 reviewed Transporter
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P53041 BXGT010968 Serine/threonine-protein phosphatase 5 5536 reviewed
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P54578 BXGT011056 Ubiquitin carboxyl-terminal hydrolase 14 9097 reviewed Enzyme
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61024 BXGT011350 Cyclin-dependent kinases regulatory subunit 1 1163 reviewed Enzyme modulator
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61088 BXGT011358 Ubiquitin-conjugating enzyme E2 N 7334 reviewed
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P67870 BXGT011566 Casein kinase II subunit beta 1460 reviewed Kinase
P78417 BXGT011843 Glutathione S-transferase omega-1 9446 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00610 BXGT012539 Clathrin heavy chain 1 1213 reviewed Transporter
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01650 BXGT012603 Large neutral amino acids transporter small subunit 1 8140 reviewed Transporter
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta 5467 reviewed Nuclear receptor
Q03403 BXGT012712 Trefoil factor 2 7032 reviewed Signaling
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q04912 BXGT012790 Macrophage-stimulating protein receptor 4486 reviewed Kinase
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07973 BXGT012952 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 1591 reviewed Enzyme
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q12797 BXGT013266 Aspartyl/asparaginyl beta-hydroxylase 444 reviewed
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13485 BXGT013363 Mothers against decapentaplegic homolog 4 4089 reviewed Transcription factor
Q13489 BXGT013364 Baculoviral IAP repeat-containing protein 3 330 reviewed Enzyme modulator
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13882 BXGT013399 Protein-tyrosine kinase 6 5753 reviewed Kinase
Q14002 BXGT013433 Carcinoembryonic antigen-related cell adhesion molecule 7 1087 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q14573 BXGT013486 Inositol 1,4,5-trisphosphate receptor type 3 3710 reviewed Ion channel
Q14749 BXGT013503 Glycine N-methyltransferase 27232 reviewed
Q14982 BXGT013518 Opioid-binding protein/cell adhesion molecule 4978 reviewed
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15717 BXGT013589 ELAV-like protein 1 1994 reviewed
Q15788 BXGT013598 Nuclear receptor coactivator 1 8648 reviewed Kinase
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16658 BXGT013651 Fascin 6624 reviewed Cellular structure
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16772 BXGT013666 Glutathione S-transferase A3 2940 reviewed
Q16878 BXGT013687 Cysteine dioxygenase type 1 1036 reviewed
Q2TU34 BXGT014223 Fructose-1,6-bisphosphatase 1 2203 unreviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q59H18 BXGT015278 Serine/threonine-protein kinase TNNI3K 51086 reviewed
Q5NUL3 BXGT015621 Free fatty acid receptor 4 338557 reviewed
Q5T6L4 BXGT015848 Argininosuccinate synthase 1 isoform 1 445 unreviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q7Z7D3 BXGT017262 V-set domain-containing T-cell activation inhibitor 1 79679 reviewed Enzyme modulator
Q86U86 BXGT017611 Protein polybromo-1 55193 reviewed Epigenetic regulator
Q8IVW4 BXGT018350 Cyclin-dependent kinase-like 3 51265 reviewed Kinase
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 22933 reviewed Epigenetic regulator
Q8ND30 BXGT018549 Liprin-beta-2 8495 reviewed
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q8WUM4 BXGT018994 Programmed cell death 6-interacting protein 10015 reviewed Receptor
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92854 BXGT019385 Semaphorin-4D 10507 reviewed Signaling
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q92905 BXGT019393 COP9 signalosome complex subunit 5 10987 reviewed Enzyme
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96FI4 BXGT019658 Endonuclease 8-like 1 79661 reviewed
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase 55872 reviewed Kinase
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q96RT1 BXGT019736 Erbin 55914 reviewed
Q99496 BXGT019925 E3 ubiquitin-protein ligase RING2 6045 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BUP3 BXGT020137 Oxidoreductase HTATIP2 10553 reviewed
Q9BXH1 BXGT020167 Bcl-2-binding component 3 27113 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C005 BXGT020207 Protein dpy-30 homolog 84661 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9H4B4 BXGT020474 Serine/threonine-protein kinase PLK3 1263 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 54575 reviewed
Q9HC97 BXGT020527 G-protein coupled receptor 35 2859 reviewed G-protein coupled receptor
Q9NRA0 BXGT021183 Sphingosine kinase 2 56848 reviewed Kinase
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NYB9 BXGT021256 Abl interactor 2 10152 reviewed Enzyme modulator
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UDY8 BXGT021670 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 10892 reviewed Enzyme
Q9UIF7 BXGT021717 Adenine DNA glycosylase 4595 reviewed Enzyme
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9UKI8 BXGT021743 Serine/threonine-protein kinase tousled-like 1 9874 reviewed Kinase
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y5N1 BXGT022297 Histamine H3 receptor 11255 reviewed G-protein coupled receptor
Q9Y5X4 BXGT022306 Photoreceptor-specific nuclear receptor 10002 reviewed Nuclear receptor
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9Y6A5 BXGT022325 Transforming acidic coiled-coil-containing protein 3 10460 reviewed
Q9Y6K9 BXGT022333 NF-kappa-B essential modulator 8517 reviewed Kinase
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
Q9Y6X9 BXGT022345 ATPase MORC2 22880 reviewed
Q9H2H9 BXGT022646 Sodium-coupled neutral amino acid transporter 1 81539 reviewed Transporter
Q92911 BXGT022650 Sodium/iodide cotransporter 6528 reviewed Transporter
P35232 BXGT022663 Prohibitin 5245 reviewed
P26045 BXGT022810 Tyrosine-protein phosphatase non-receptor type 3 5774 reviewed
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
P17752 BXGT023118 Tryptophan 5-hydroxylase 1 7166 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P40198 BXGT023750 Carcinoembryonic antigen-related cell adhesion molecule 3 1084 reviewed
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
Q9HCK4 BXGT024280 Roundabout homolog 2 6092 reviewed
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
Q9GZV5 BXGT025439 WW domain-containing transcription regulator protein 1 25937 reviewed Enzyme modulator
Q9UGM3 BXGT025543 Deleted in malignant brain tumors 1 protein 1755 reviewed Enzyme
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
Q86SG6 BXGT026136 Serine/threonine-protein kinase Nek8 284086 reviewed Kinase
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease