Showing entry for Osteoarthrosis Deformans


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003308
Disease NameOsteoarthrosis Deformans
Disease CUI IdC0086743
MeSH Codes C05  
Disease Class NameMusculoskeletal Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00217 BXGT003898 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial 4728 reviewed Enzyme
O00299 BXGT003905 Chloride intracellular channel protein 1 1192 reviewed Ion channel
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O00560 BXGT003937 Syntenin-1 6386 reviewed Transporter
O00571 BXGT003938 ATP-dependent RNA helicase DDX3X 1654 reviewed
O43854 BXGT004630 EGF-like repeat and discoidin I-like domain-containing protein 3 10085 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P08559 BXGT006788 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 5160 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P10768 BXGT007611 S-formylglutathione hydrolase 2098 reviewed Enzyme
P10909 BXGT007630 Clusterin 1191 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P13637 BXGT007933 Sodium/potassium-transporting ATPase subunit alpha-3 478 reviewed Transporter
P13639 BXGT007934 Elongation factor 2 1938 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P20618 BXGT008589 Proteasome subunit beta type-1 5689 reviewed
P21399 BXGT008646 Cytoplasmic aconitate hydratase 48 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27348 BXGT009173 14-3-3 protein theta 10971 reviewed Chaperone
P30153 BXGT009409 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 5518 reviewed Enzyme
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49821 BXGT010748 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 4723 reviewed
P50213 BXGT010779 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 3419 reviewed Enzyme
P52895 BXGT010961 Aldo-keto reductase family 1 member C2 1646 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62826 BXGT011463 GTP-binding nuclear protein Ran 5901 reviewed Enzyme modulator
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q04828 BXGT012787 Aldo-keto reductase family 1 member C1 1645 reviewed Enzyme
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q6NVY1 BXGT016432 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 26275 reviewed Enzyme
Q8IVL6 BXGT018347 Prolyl 3-hydroxylase 3 10536 reviewed Extracellular structure
Q8WUM4 BXGT018994 Programmed cell death 6-interacting protein 10015 reviewed Receptor
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
P19875 BXGT023294 C-X-C motif chemokine 2 2920 reviewed Signaling
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease