Showing entry for Sodium-coupled neutral amino acid transporter 3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019942
Protein NameSodium-coupled neutral amino acid transporter 3
Uniport IdQ99624
GeneSLC38A3
Gene Id10991
Domain_trans
Pfam PF01490  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
5. Organismal Systems 5.6 Nervous system hsa04727 GABAergic synapse
5. Organismal Systems 5.5 Excretory system hsa04964 Proximal tubule bicarbonate reclamation
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0003333 amino acid transmembrane transport
Biological Process GO:0006865 amino acid transport
Biological Process GO:0006867 asparagine transport
Biological Process GO:0007420 brain development
Biological Process GO:0051365 cellular response to potassium ion starvation
Biological Process GO:0007565 female pregnancy
Biological Process GO:0006868 glutamine transport
Biological Process GO:0015817 histidine transport
Biological Process GO:0015808 L-alanine transport
Biological Process GO:2000487 positive regulation of glutamine transport
Biological Process GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
Biological Process GO:0006814 sodium ion transport
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015297 antiporter activity
molecular function GO:0015180 L-alanine transmembrane transporter activity
molecular function GO:0015182 L-asparagine transmembrane transporter activity
molecular function GO:0015186 L-glutamine transmembrane transporter activity
molecular function GO:0005290 L-histidine transmembrane transporter activity
molecular function GO:0015293 symporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0220981 BXGD004348 Metabolic acidosis Nutritional and Metabolic Diseases
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0376618 BXGD008003 Endotoxemia Pathological Conditions, Signs and Symptoms; Infections
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0856169 BXGD011096 Endothelial dysfunction
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1857586 BXGD015719 CONOTRUNCAL HEART MALFORMATIONS (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000458 L-Asparagine 132.12
BXGC0031608 Histidine 155.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein